Does Alzheimer’s Disease Have Three Stages or Seven Stages?

How many stages does Alzheimer's actually have?

Alzheimer’s Disease is a specific condition that, in its most generic form, is referred to as dementia. There are numerous sorts of dementia, but each are characterized by severe impairment of cognitive (or mental) function – including diminishment of memory and reasoning ability – resulting in extreme states of physical and social incapacity. Different dementias may be precipitated by different causes, but Alzheimer’s is basically describable as a degenerative brain disease, usually (but not always) occurring in seniors, in which various protein deposits (called “plaques” or “tangles”) accumulate in, and destroy, brain tissue. And this deterioration occurs progressively, in stages.

But just how many such “stages” does Alzheimer’s have, three or seven Both! Alzheimer’s has three basic stages: (1) early, (2) middle, and (3) late – corresponding to the familiar storytelling categories: beginning, middle, and end. You can get seven stages by making a few additional distinctions. Thus, the expanded list is: (1) no impairment, (2) very mild cognitive impairment, (3) mild cognitive impairment), (4) mild Alzheimer’s, (5) early-moderate stage Alzheimer’s, (6) moderate Alzheimer’s, (7) severe Alzheimer’s.

Some lists talk of three stages, while others speak of seven. Which is it?It is arguable that classifying an Alzheimer’s patient into a particular stage involves a bit of educated guesswork. In broad terms, Alzheimer’s can be thought of as occurring in three stages. But some observers have attempted to carve out finer distinctions, resulting in the creation of several additional stages, yielding seven. (Or…maybe it has five stages! See below.) However, while these systems may seem different at first glance, there are ways of reconciling them.

But, seriously, for additional analysis, criticism, and details, read on. Let me explain.

The Three-Stage System

Arguably, the most widely repeated and used classification system is (one version of) a three-stage view of Alzheimer’s decline. It is the one promulgated by the powerhouse Alzheimer’s Association, through its flagship website.[1] And, let’s face it, with only three classification categories, the system is just plain easy to remember.

The standard enumeration of this three-stage system is straightforward.

The Standard, Three-Stage View of Alzheimer’s

  1. Beginning/Early Stage
  2. Middle Stage
  3. End/Late Stage

As I mentioned in my introductory remarks, part of the appeal of this way of categorizing the progression (or, rather, regression) of Alzheimer’s dementia is that it somewhat neatly corresponds to way in which we are used to stories being told.

And, in a sense, this categorization schema basically helps people tell the story of a particular Alzheimer’s patient’s personal struggle with the disease. The immediate utility of the approach is that, upon hearing the stage, one immediately knows where the sufferer is in his or her story of decline – at the start, at the finale, or somewhere in between.

Symptoms map fairly intuitively – even if somewhat vaguely – onto the three stages.

For example, if your loved one needs little to no help with daily living, then he or she would fit most neatly into the “early stage.” As soon as assistance for the so-called “activities of daily living” reaches a predetermined threshold (specifically, lacking two out of six, for more information on which see this ARTICLE and this VIDEO), then for all intents and purposes the person is well into middle stage. The final or “end” stage of the disease occurs when impairment is so severe as to prevent locomotion and, later, cease or impede more basic bodily functions such as coughing and swallowing.

What to Expect at Each of the Three Stages

As the Merck Manual puts it: “In Alzheimer’s disease, parts of the brain degenerate, destroying cells… Abnormal tissues, called senile plaques and neurofibrillary tangles, and abnormal proteins appear in the brain…”.[2] Because this deterioration may affect different parts of the brain in different sufferers, the symptoms of Alzheimer’s are prone to vary from person to person. However, there are recognizable patterns of changes that are fairly stable.

I will break the relevant changes into four categories: changes affecting cognition, daily living, memory, and personality. Just a word of caution. The categories are not necessarily mutually exclusive; nor  are the various symptoms neatly divisible into the categories.

Presently, I will give you a sense of what these four categories of change might look like across the three stages of Alzheimer’s just canvassed.

Changes in Early-Stage

Cognitive Changes in Early Stage

As Alzheimer’s begins, high-level changes are minimal. Most function remains intact, but there are a few areas of concern.

Number one, sufferers in early stages of Alzheimer’s may begin to experience difficulty with so-called “abstract thinking” – that is, thinking about ideas and abstract objects (e.g., numbers, propositions, sets). They may therefore have trouble with such activities as doing mathematics problems or otherwise manipulating numbers. It is, however, vitally important to take a person’s “baseline” into account. In other words, a person’s present abstract-thinking abilities must be assessed against the abilities that they had five years ago, ten years ago, etc. The pertinent thinking difficulties are relative to an individual’s prior capabilities.

Number two, early-stage Alzheimer’s patients arguably start to lose some of their language faculties. But as this is first and foremost evidently a memory problem, I will cover it below.

Daily-Living Changes in Early Stage

In such fields as long-term-care insurance and senior healthcare, one important concept is the definition of the “Activities of Daily Living,” or ADLs.[3] I go into much greater detail on the ADLs in THIS ARTICLE and THIS VIDEO. Suffice it to say that there are six of them – bathing oneself, dressing oneself, feeding oneself, maintaining one’s continence, toileting by oneself, and transferring in and out of bed by oneself – and that losing the ability to perform two out of the six qualified a person as “long-term care” needy. Additionally, having diminished cognitive capacity – and requiring supervision – can also trigger the need for long-term care.

As far as the ADLs go, early-stagers are usually in pretty good shape. At least, they’re not too badly off in terms of their mental decline. It is always possible that a given patient also sufferers from ailments, conditions, or diseases in addition to Alzheimer’s and that these comorbidities affect the person’s ability to perform one or more ADLs quite separately from the dementia.

In the early stage, many Alzheimer’s-afflicted individuals can or will still enjoy some measure of independence. They are frequently still able to perform the ADLs and their sleep patterns remain largely unaltered by their conditions.

Memory Changes in Early Stage

As noted, above, some there are sometimes hints of looming language problems in early stage. However, these are often confined to the remembrance of things like names and other words. It is sometimes said that early-stage dementia sufferers have a word on the tips of their tongues, as it were, but are unable to bring it back.

Patients may also forget instructions or plans, and they may lose items.

Personality Changes in Early Stage

Now if you are breaking into cold sweats looking at the list of changes, thinking, “Oh, no! I Forget words and lose objects and struggle to do math… I must be in the early stages of Alzheimer’s!” Take heart.

For this final category of change is often the one that makes the presence of dementia the most apparent – and poignant. This is the group of changes that affect a person’s personality. My dad, Jim, for instance, was always the sweetest guy. But as his Alzheimer’s progressed, he became belligerent, suspicious, and unpleasant. (Read about Jim’s experiences HERE.)

In early stages, however, changes may not yet be that dramatic. A person may simply become somewhat more awkward in social situations than he or she had been previously. Or certain – possibly latent or recessed – personality tendencies may suddenly start to get more pronounced.

Changes in Middle Stage

Cognitive Changes in Middle Stage

During middle stage, language abilities take a major hit. Reasoning processes become more muddled.

Other cognitive changes dovetail with personality changes, about which read more further on.

Daily-Living Changes in Middle Stage

The sufferer’s abilities to perform the ADLs also declines sharply through middle stage. The affected individual may bathe infrequently and inadequately, for instance. And the person may begin to behave erratically and unreliably in the bathroom.

To illustrate, my dad would sometimes confuse various paper products – facial tissues, paper towels, toilet paper, etc. – with potentially messy results that I will leave to readers’ imaginations.

The capability of dressing oneself may or may not remain. In some cases, the mechanical ability to put on clothes is present, but – because of decreased awareness, judgment, and so on – a person loses the good sense to choose appropriate garments for the occasion or for the weather.

Sleeping may also begin to go haywire. My dad would often be awake late into the night, and he would frequently nap at odd times during the day. Some of this might be treatable with sleep aids or coffee.

Memory Changes in Middle Stage

As the Alzheimer’s worsens, sufferers begin to have difficulty remembering personal information – address, social-security number, telephone number, and so on. They will also tend to have trouble recalling newly acquired information and recent events.

A person may also begin to “elope” from his or her residence and wander around. In my dad’s case, it sometimes seemed to me that he was “testing” his memory by leaving and seeing if he could find the way back. However, it is also possible that he (and other patients) merely begin to leave with some poorly conceived plan or purpose but then forget those things along the way and end up roaming about aimlessly.

Personality Changes in Middle Stage

At this stage of things, a personality might have diverged considerably from what family and friends were used to. The nature of these changes is prone to variation. But anecdotally, I have found that numerous caretakers and relatives relate that their loved ones either became more aggressive or docile than they had been. My dad became the former.

Still, many Alzheimer’s sufferers will be moody, and their demeanors will shift – sometimes without much warning.

Alzheimer’s-affected people may withdraw entirely from social interactions. And they may be delusional or even paranoid. I have frequently related that my dad accused my children and me of stealing from him (among other allegations).

Excursus: Ambulation, Family Recognition, and ‘Sundowning’

Somewhere in the hazy nexus between middle and late stages, three other things may become issues for your loved one – as they were for my dad.

Ambulation

“Ambulation” is a ten-dollar word for “walking.” In my dad’s case, as his Alzheimer’s progressed – and, frankly, as his nursing-home caretakers more heavily medicated him – he lost the ability to “ambulate.” He became “non-ambulatory,” meaning that he went from being able to walk around to being unable to do so.

This is a considerable and serious change. This is so not only because of the diminishment of the faculties and personal independence that it represents, nor even because of the terminal stage that it portends – which is scary, indeed. (On Alzheimer’s as a terminal illness, see HERE.) But the loss of mobility also increases the patient’s risk for secondary health problems such as blood clots and pneumonia.

Family Recognition

Another striking facet of this murky degenerative process is the ultimate obliteration of an Alzheimer’s sufferer’s ability to recognition close family and friends. Whether this is based upon the destruction of a person’s memories regarding faces, voices, and personalities or whether it is grounded in something else (e.g., a malfunctioning perceptual apparatus, or awareness gone berserk) is unknown. But, at some calamitous and sad point, it appears as though certain Alzheimer’s sufferers will lose their abilities to even acknowledge or identify people who were – and are – of great importance in their lives.

‘Sundowning’

“Sundowning” is a rather odd phenomenon that my family was introduced to after my dad was in the hospital for triple-bypass surgery. It refers to a condition – likely a byproduct of the changes brought on by Alzheimer’s – whereby a person becomes more confused as the day progresses. In other words, some dementia sufferers are more difficult to handle and more disoriented in the evening hours than they are earlier in the day.

Whether this has anything to do with sunlight exposure is unknown. But for an intriguing link between Alzheimer’s Disease and vitamin-D deficiency, see HERE and HERE.

Changes in Late Stage

Cognitive Changes in Late Stage

Perhaps the most tragic change to occur in late stage is that communication dwindles to virtually nothing. In some cases, an Alzheimer’s sufferer may seemingly become totally unresponsive to external stimuli.

Daily-Living Changes in Late Stage

Changes in this category escalate dramatically. Many times, in late stage, ability to perform any of the ADLs drops away entirely. To put it slightly differently, and due to compromised fine-motor skills, patients lose the ability to self-dress.

The also tend to lose the ability to feed themselves. And this occurs as a gloomy precursor to the loss of even more basic life functions, such as the ability to swallow food and water.

Moreover, late-stage Alzheimer’s patients typically experience near complete degradation of their mobility, to the point where they can no longer transfer in and out of bed on their own power. Indeed, many individuals lose the ability to even do something as simple as sit upright.

In this end phase, infections (like pneumonia, sepsis, and urinary-tract infections) become all too common. Sometimes death comes through these – or similar, attendant conditions like blood clots.

For more information on how Alzheimer’s sufferers die, as well as on what constitutes a “terminal illness,” see articles HERE and HERE, as well as THIS VIDEO.

Memory Changes in Late Stage

At this point in the process of devolution, memory is seriously eroded or otherwise undermined. The patient may only recall distant memories, if even those. Basic awareness and perception are either extremely weakened or entirely absent.

Personality Changes in Late Stage

Even the exaggerated and somewhat caricatured personality traits of the succeeding stages melt away into oblivion. It can feel as though the person you knew has essentially disappeared.

Affect is often flat, and your loved one may (appear to) be completely emotionless.

Caveat: Categorization Is Not an Exact Science

However, as I have stated elsewhere (see my brief overview of Alzheimer’s, HERE), there is not a little guesswork that goes into actually categorizing a person into a stage. Citing “overlap,” the Alzheimer’s Association warns readers to be mindful of the fact that “…it may be difficult to place a person …in a specific stage…”.[4]

One problem is really ambiguity or “fuzziness” in the in-between areas.[5]

So, for instance, based solely upon mini-cognitive examinations (for a bit more on which, see this ARTICLE and this VIDEO) it may be somewhat difficult to say when, precisely, a person goes from simple, age-related forgetfulness to clinical impairment or dementia.

There are a number of possible reasons for this imprecision. If you’re interested in my opinion, you can read a few of my speculations in the APPENDIX at the bottom of this page. They may give you a sense of what I believe to be the complexity inherent in this issue. If you’re not interested – and that’s okay! – then just keep moving down to the next section, where I get into enumerations of the seven-stage view.

The Seven-Stage System

As just previously noted, the whole Alzheimer’s-classification thing is sort of fuzzy around the edges. (For more commentary on this, see the “Appendix,” at the bottom of the page.) In fact, as has been alluded to, even the choice of schema leaves not a little bit to personal (or professional) preference. However, this is probably to be expected, given the incomplete state of our knowledge about the disease. (For an overview of Alzheimer’s, see HERE.)

This is not meant to be an indictment of the categorization process. But it is something I think that you should be aware of.

Dissatisfaction With the 3-Stage View

Some people have apparently been dissatisfied with the three-stage view. The most intuitively obvious criticism of the three stages might be that they paint with too broad a brush. To put it another way, Alzheimer’s is a disease that causes brain and cognitive degenerative over years, or even over decades. The changes can be somewhat gradual. Some people might worry, then, that a categorization system that only uses three stages might be a bit too clumsy and overly general to apply to such a lengthy process of deterioration.

With only three stages, an Alzheimer’s-afflicted person must fit into one of the three. But you may find people with widely varying abilities and deficits sharing the “same stage.”

For example, even though the transitions are hard to pin down, a person who has just entered “middle stage” will be a little worse than (but still somewhat close to) a person who is still in “early stage.” But a person whose regression is getting so severe that he or she is about to enter “late stage” will be much worse off – and yet will still be in “middle stage.”

The result is that you can have two people – both in “middle stage” – who have very different sets of abilities and needs. And this might seem to be a poor way to classify patients.

And this same problem can probably be retooled to apply to all three of the stages. For instance, my dad basically went through the entirety of “late stage.” At the beginning of this stage, he had pretty well lost the ability to communicate and walk and he was nearly continuously struggling with some infection or other. But, by the end, he lost the ability to swallow food and water and, eventually, was only able to lie in bed, having lost the ability to sit upright. He looked very different at the beginning of late stage and at the end of it. So, again, the question is: Is it really meaningful to think of both as being the same stage?

7 Stages as a Modification to the 3-Stage View

Now, one possible way to salvage the three-stage view would be to start referring to grades within each stage. So, instead of speaking about “middle stage, [period],” you might talk instead of “early-middle stage” or “late-middle stage.” So, for instance: My dad, sitting and smiling, but unable to talk or care for himself was in “early-late stage.” But my dad lying there, unable to swallow food or water was in “late-late stage.” Or something like this.

But by this time, a person might reasonably ask: do we really have a three-stage view anymore? If you are going to add qualifiers to every stage, why not just carve out a few more stages?

I am not entirely clear on the history, here, but presumably, the seven-stage view was an outgrowth of this kind of reasoning process.

Even here, though, variations abound. Just as with the three-stage view, the seven-stage system has its variants as well. (See further down this post for the details.) My research suggests that when a seven-entry catalog is used, it generally represents the stages as follows.

The Standard, Seven-Stage View of Alzheimer’s

  1. No Impairment
  2. Very Mild Decline
  3. Mild Decline
  4. Moderate Decline
  5. Moderately Severe Decline
  6. Severe Decline
  7. Very Severe Decline

This articulation of the stages was apparently devised by academics Barry Reisberg and Emile Franssen[6] and seems to be preferred by authority sites such as Alzheimers.net.[7] Additionally, it is repeated, or reproduced on a website called CaregiverHomes.[8]

And the seven stages are presumably supposed to give us a bit more precision in classifying a person into a stage. However, as with the three-stage view, it may not always be totally clear in which of the seven stages, exactly, a given patient falls. But let’s look at what the seven-stage view adds.

Differences Between the 3- & 7-Stage Views

The first addition is a stage dedicated to a state of “no impairment.” This may seem somewhat strange, since it implies that – on this particular scale – everyone is at least in “Stage 1” of Alzheimer’s. I’m not entirely sure that I find it helpful to include a category that – as far as I can tell – basically doesn’t distinguish between a normal 65-year-old who will, as it turns out, develop Alzheimer’s in ten years and a newborn baby who won’t develop any sort of dementia for decades (if ever).[9]

Skipping Stage 2 for the moment, I note that the inclusion of a Stage 3 seems more understandable. In an alternative exposition of the seven stages (see the relevant section, below), “Mild Decline” is identified with a condition that has come to be known as “Mild Cognitive Impairment,” or MCI. According to standard opinion, this condition is actually diagnosable by a doctor and it is often a prelude to full-blown Alzheimer’s. Therefore, it makes some sense to include it as a “stage” of Alzheimer’s – even though it is by no means certain that a person with MCI will develop Alzheimer’s.

One Mayo Clinic article flatly declares that MCI “may increase your risk of later developing dementia caused by Alzheimer’s disease or other neurological conditions. But some people with mild cognitive impairment never get worse, and a few eventually get better.”[10] Some commentators speak merely of the “likelihood of progression from MCI to Alzheimer’s,”[11] which implies that the link is one of probability as opposed to inevitability.

So, even though the inclusion of this Stage 3 makes some sense, it is still a bit puzzling. After all, if you have a diagnosis of MCI it may be misleading to think of yourself as being in “Stage 3 of Alzheimer’s” if it is true that you may never develop Alzheimer’s – or even that you may improve.

Stage 2 is also a little peculiar. According to presentations of the seven-stage system, Stage 2 is unlikely ever to be recognized while a person is in it. For example, in the explanation of this stage given by the folks at Alzheimers.net, we read that “the disease is unlikely to be detected by loved ones or physicians.”[12]

You have to realize, therefore, that the seven-stage system has several listed stages that you will probably only be able to assign to yourself or your loved one in retrospect.

Take my dad’s case. My dad, Jim, wasn’t diagnosed with Alzheimer’s until he was in middle stage – on the three-stage view. Assuming that, in seven-stage lingo, he had “moderately-severe decline” by this time, he would have been at (or around) Stage 5 on the longer scale.

To put it differently, my dad’s Alzheimer’s wasn’t recognized right away. Thus, it is important to note that regardless which of the two scales you prefer, my dad’s Alzheimer’s advanced with at least one stage being unnoticed.

The only thing that I would say is that it seems on the three-stage view, it would have theoretically have been possible to actually identify my dad as having been in “Early Stage Alzheimer’s” while he was in it. Granted, it was missed in my dad’s case. But this wasn’t a deficiency of the scale. It was a deficiency of the observers, who failed to recognize or properly identify the signs.

On the other hand, on the seven-stage system, it appears as if Stage 3 is the earliest stage that could actually be recognized for what it is — at least, while a person is in it. And, as we have seen, Stage 3 may not progress into Alzheimer’s at all.

To summarize the additions we’ve addressed so far:

  • Stage 1 applies to everybody who isn’t already classified in a higher stage.
  • Stage 2, practically by definition, will go unnoticed.
  • Stage 3 may be noticed but may not actually develop into Alzheimer’s.

But this seems to mean that the first three stages of the seven-stage system arguably don’t add much of use to the three-stage system.

Stage 4 gets us into bona fide Alzheimer’s. But, by this time, the patient would likely be in “early stage” on the three-stage system.

Once we get to this point, the sevenfold taxonomy now provides us with four stages (4, 5, 6, & 7) for categorizing patient’s Alzheimer’s status. Apart from the first three stages, which may or may not be of interest, this additional stage does seemingly give the seven-stage view an advantage over its three-stage counterpart.

How the Three- and Seven-Stage Systems Fit Together

Logically (if not chronologically or historically), the usual way of unpacking seven stages is perhaps best thought of as an expansion of – or an elaboration upon – the three-stage system.

Indeed, as readers probably noticed, the three stages (from the three-stage list) are pretty obviously included within the seven stages. On this way of thinking about the systems, essentially, the seven-stage view merely adds on four stages to the briefer threefold articulation.

However, these additions and expansions need not be thought to generate an entirely novel or divergent classification system. In other words, there are ways of combining the two systems.

One approach, taken by the aforementioned CaregiverHomes website, is to embed the three stages from the shorter taxonomy into the sevenfold system.

This might look like the following. On the left, I name the relevant stage from the three-stage approach, and then, on the right, I provide the corresponding stage(s) from the seven-stage approach.

  • [Stage from Threefold View: NONE (Preclinical Alzheimer’s)[Stages from Sevenfold View: 1-3]
  • [Stage from Threefold View: Early Alzheimer’s)]→[Stage from Sevenfold View: 4]
  • [Stage from Threefold View: Middle Alzheimer’s)]→[Stages from Sevenfold View: 5-6]
  • [Stage from Threefold View: Late Alzheimer’s)]→[Stage from Sevenfold View: 7]

Are There Alternative Classification Systems?

A Two-Stage System

Theoretically, a simple two-stage schema can be formed by linking the idea of a pre-symptomatic first stage with a symptomatic second stage.

Simple 2-Stage Formula

  1. Pre-symptomatic Stage
  2. Symptomatic Stage

It is highly doubtful that such a characterization of the disease is of much use for caretaking or diagnostic purposes. But there may be certain clinical or research contexts in which the only relevant fact is whether a subject is pre- or post-symptomatic.

Alternative Three-Stage Systems

An Expanded Two-Stage Approach

The first alternative to the standard (early, middle, late) three-stage view is basically the simple, two-stage view with an intermediate stage added that allows for stage two to be divided into two parts. (And, maybe there’s one additional little change.)

Sometimes this median stage is designated by the rather cryptic word “prodromal.” The so-called prodromal stage, number one, is that which lies in between the pre- and post-symptomatic stages. But, number two, it is also a particular kind of “symptomatic stage.” Namely, the “prodromal” stage is that in which “memory is deteriorating but a person remains functionally independent.”[13]

So, the initial “symptomatic stage” is therefore also replaced by a stage that complements the prodromal stage. To be precise, the third stage becomes one in which the person is no longer functionally independent.

This version of the three-stage view would look something like this.

‘Functional’ Three-Stage View

  1. Pre-symptomatic Alzheimer’s
  2. Prodromal Alzheimer’s – Memory is Negatively Affected, But Person Functions Independently
  3. Nonfunctional Alzheimer’s – Both Memory and Daily Function are Deteriorated

Three Stages as Losses of Psychological Powers

The ancient Greek philosopher Aristotle (384-322 B.C.E.) wrote a book that has come to us better known by its Latin title, De Anima (ca. 350 B.C.E.), meaning “On the Soul.” In fact, the Greek word for “soul” was psyche (or psuchē). The word persists in our day in our science of psychology – which, to an ancient, would designate the “study of the soul.”

But, just as the science of psychology does not attribute religious or supernatural qualities to the psyche, so too in this work does Aristotle assume a more or less “neutral” definition of “soul.” Stemming back to at least to Plato, psyche basically just meant “life force.”[14] And that minimalistic definition will suffice for what follows.

Aristotle recognized three levels of life force, pertaining to plants, animals in general, and human animals in particular. He distinguished them in virtue of what have come to be called “powers” of the soul.[15]

So, at the level of plant life, Aristotle thought, there was a “nutritive” or “vegetative” soul. This life force was evident in virtue of a plant’s ability to grow, “nutrify” itself – by drawing upon soil, sunlight, and water – and to reproduce.

A bit higher up are the animals, enjoying an “animal” or “sensitive” soul. This life force has all the nutrifying and reproductive abilities of a plant alongside certain locomotive and appetitive powers that allow animals to move from place to place (unlike plants) and to experience sensations.

Finally, there are humans, who have “human” or “rational” souls. As before, the human life force subsumes all the powers of plants and animals – mobility, nutrition, reproduction, sensation, etc. But human beings also have rational faculties that allow us to be capable of reasoning, reflecting, remembering, and so forth.

With that much groundwork in place, I will observe that it is possible to think of Alzheimer’s stages in Aristotelian terms. To be more exact, Alzheimer’s can be thought of as progressively stripping an individual of “soul powers,” so to speak. There are three layers, corresponding to the rational, animal, and nutritive qualities of the human life force, as briefly sketched above. This creates a kind of three-stage Aristotelian view of the decline of Alzheimer’s that can be roughly represented as follows.

3-Stage ‘Aristotelian’(-Inspired) View

  1. Loss of Rationality – Cognition, Memory, Etc.
  2. Loss of Animality – E.g., Locomotion
  3. Loss of ‘Nutritivity’ – Ability to Sustain One’s Own Life & Bodily Functions

Put somewhat colorfully, the basic – and tragic – idea is that Alzheimer’s dementia systematically strips away various physiological-psychological powers, leaving the sufferer without even the basic nutritive capabilities of a plant. It may work better as a metaphor than as a literal description of the effects of the disease, but I think it is evocative.

Alternative Seven-Stage System

There are several slight variations on the seven-stage system. Each of them shares fundamental similarities, however. For example, the website Healthline (HL) gives a slight variation on the sevenfold enumeration sketched in a previous section.[16] (See above.)

HL’s Alternative Seven-Stage Breakdown

  1. No Impairment
  2. Very Mild Cognitive Impairment
  3. Mild Cognitive Impairment
  4. Mild Alzheimer’s
  5. Moderate Alzheimer’s
  6. Moderately Severe Alzheimer’s
  7. Severe Alzheimer’s

The first stage – “No Impairment” – is identical to that given by AN. Here, however, the words “cognitive impairment” is used in the second and third stages, as opposed to the employment of the word “decline.” Otherwise, in the first three stages, the systems are in agreement with respect to their adjectives.

At Stage 4, though, we begin to see a few slight differences. In AN’s version, Stage 4 is labeled “Moderate Decline,” whereas HL names the same stage “Mild Alzheimer’s.” I suppose that the idea is that mild Alzheimer’s is characterized by moderate (cognitive) decline, and so these should come down to the same thing.

Similarly, AN’s Stage 5, labeled “Moderately Severe Decline,” is presumably supposed to convey the same idea as HL’s “Moderate Alzheimer’s.” Readers will probably be struck with the fact that these words – including “decline” and “impairment” as well as “mild,” “moderate,” and “severe” – are somewhat artful, as they appear to lack precise diagnostic criteria.

Again, at Stage 6, we may compare AN’s “Severe Decline” with HL’s “Moderately Severe Alzheimer’s.” Apparently, we are to understand that moderately severe Alzheimer’s is distinguished by severe cognitive decline.

Finally, AN’s “Very Severe Decline” apparently corresponds with HL’s “Severe Alzheimer’s.”

Frankly, I can’t help getting the impression that these authors – however well-intentioned – are battling more over English modifiers than they are disputing about Alzheimer’s symptoms. And this impression is underscored when I look at another – basically, identical – list, this one from Very Well Health (VWH).

VWH’s Seven-Stage System

  1. Absence of Impairment
  2. Minimal Impairment
  3. Noticeable Cognitive Decline
  4. Early-Stage/Mild Alzheimer’s
  5. Middle-Stage/Moderate Alzheimer’s
  6. Middle-Stage/Moderate to Late-Stage/Severe Alzheimer’s (sic)
  7. Late-Stage/Severe Alzheimer’s

The similarities between this list and the previous two are probably not worth tediously rehearsing. It is arguable, though, that the addition of the word “noticeable” in this rendition of Stage 3 is supplied in deference to the fact (stated earlier) that Stages 1 and 2 are pretty much undetectable.

VWH’s list seems to have been drafted to combine the verbiage of the three- and seven-stage systems, possibly in an effort to aid comprehension. (Or possibly just to create feelings of familiarity in people regardless of which system they are accustomed to.)

Seven-stage views of Alzheimer's.
Side-by-side view of three of the main 7-stage Alzheimer’s -classification schemes.

A Five-Stage System

Believe it or not, there is another way of reckoning the various stages of Alzheimer’s. It comes from the prestigious Mayo Clinic, no less.

“There are five stages associated with Alzheimer’s disease: preclinical Alzheimer’s disease, mild cognitive impairment due to Alzheimer’s disease, mild dementia due to Alzheimer’s disease, moderate dementia due to Alzheimer’s disease and severe dementia due to Alzheimer’s disease.”[17]

Mayo Clinic’s 5-Stage System

  1. Preclinical Alzheimer’s
  2. Mild-Cognitive Impairment due to Alzheimer’s
  3. Mild Dementia due to Alzheimer’s
  4. Moderate Dementia due to Alzheimer’s
  5. Severe Dementia due to Alzheimer’s

Actually, since the initial question was “Does Alzheimer’s Have Three or Seven Stages?” it might seem somewhat odd for me to end by saying, “Maybe it has five!” I hope readers have detected by now my skepticism that a definite number of “stages” can be fixed upon. But, the five-stage view – particularly this articulation of it – does have several things to commend it.

Number one, the tag-on line “due to Alzheimer’s,” performs real work. For instance, one criticism against the seven-stage system’s reference to “mild cognitive impairment” was that MCI does not necessarily develop into Alzheimer’s. But, here, the Mayo Clinic writers rebut this by qualifying the sort of MCI that they have in mind. They’re not just talking about any old MCI. They’re talking about MCI due to Alzheimer’s. I don’t know whether MCI can be distinguished like this – in advance, anyway. But it is an admirable attempt to address this sort of criticism.[18]

Number two, the system begins with “Preclinical Alzheimer’s.” This, to my mind, seems a much more reasonable starting place for a list of Alzheimer’s stages than does the sevenfold systems’ mention of a “no-impairment” stage that basically applies to everyone from infants in diapers to high schoolers, collegiates, and basically everyone who isn’t already in a further stage.

Conclusion

I am skeptical that there is a definite – let alone identifiable – number of “stages” that every and all Alzheimer’s patient goes through. I am even skeptical of the lesser claim that there is a fact of the matter about the number of stages that an Alzheimer’s patient would go through if he or she lived through an entire progression of the disease.

Firstly, I just don’t think that Alzheimer’s disease itself works like this. Alzheimer’s is a brain-degenerating disease. And, presumably, it affects different parts of the brain in different people. So, in the first place, it seems plausible to think that a person’s experience with Alzheimer’s – and his or her “stages” of decline – will be highly individualistic or idiosyncratic or however you want to put it. They will be particular to him or her.

Secondly, I just don’t think that words like “mild,” “moderate,” “severe,” or for that matter “stages” are precise enough to do the classificatory work desired, expected, or hoped for. There is a vagueness that attends to each of these. And insofar as the various categorization approaches just string these words together, it seems to follow that there is a vagueness that permeates the whole project.

But this is emphatically not to say that there is not utility to classifying Alzheimer’s patients or to trying to track their declines. There surely is great benefit to this.

So, keep your favored system. Learn about it. Study it. And apply it. Perhaps, though, it would be best not to be doctrinaire about your preferences. It is probably the case that all the systems surveyed are good enough for their own purposes. And many times the purposes for systems will vary.

Appendix

Six Reasons Why It Is Difficult to Pin Down A Stage

  1. Self-reporting. This is hardly unique to cognitive dementia tests. Rather, it attends – to one degree or other – to virtually any examination that depends upon people talking about how they feel. In a word, people are unreliable. They can be misleading or mistaken – and that’s just for starters.
  2. Question limitations. Another difficulty lies in the cognitive-examination questions themselves. Questions typically ask about areas of common knowledge, like the days of the week or the letters of the alphabet. However – and I am no neuroscientist – it seems to me that insofar as Alzheimer’s is characterized by brain deterioration, and insofar as different areas of the brain might be affected in different patients, it may be that some patients’ impairments will not be identified by these sorts of questions. Possibly this will be because parts of their brains are impacted other than the parts that store the answers to these questions.
  3. Alternating lucidity and murkiness. Another factor is that Alzheimer’s sufferers typically swing from periods of clarity to periods of cloudiness. From interacting with my dad, Jim, I remember that there will be times when he would not be able to answer a particular question that would be followed by times where he would be able to. And this cycling can go on for many years. One reason why Jim’s physician didn’t recognize his Alzheimer’s as early as would have been desired was probably due to this very fact. My dad just happened to be more lucid during doctor’s appointments than he was when it began to be apparent to the family that something was off.
  4. Lifestyle variations. And this, it seems, sort of segues into another possibility difficulty. Namely, different people live different types of lives and surround themselves with different types of people. Whereas, in the year or so before my dad was officially diagnosed, I had the opportunity to observe him closely – and I had the ability to research Alzheimer’s symptoms and compare them with my dad’s behaviors – other Alzheimer’s sufferers may not live or interact with people who are able or willing to perform similar roles for them. Things can go unnoticed, unrecognized, or neglected.
  5. Baseline differences. Yet another sticky area involves the intuitive fact that people have different vocabularies and levels of intelligence. If this is so, though, then it’s not enough to say that a person’s cognitive abilities are at some particular level, say “level x” (whatever x happens to be). To get a truer picture, observers must actually be able to compare the subject’s cognitive abilities against his or her baseline – that is, the cognitive level that he or she was at before any (suspected) impairment surfaced. But this assumes a level of personal knowledge and past dealings between observer and subject that may not exist.
  6. Vague diagnostic categories. Finally, and I am no medical professional, but it also seems to me that there is a bit of fuzziness built into the lists of symptoms to watch out for. The Alzheimer’s Association, for example, says that early-stage Alzheimer’s will be characterized by things like a person struggling to “[come] up with the right word or name” in a given situation or “[l]osing …a valuable object”.[19] Firstly, and surely, these symptoms comes in degrees. But, secondly, qualifier such as “right” and “valuable” are not a little vague themselves.

Don’t get me wrong. I’m not saying that the diagnostic situation is hopeless. I’m simply suggesting that it is difficult. It’s not easy to say, on the basis of cognitive tests alone, that a person has or doesn’t have the beginnings of bona fide dementia.

Fuzzy at the Edges; Clearer in the Center

These problems of vagueness abound in language, philosophy, and psychology. To hearken back to the discussion I had HERE, perhaps the best we can say is that even though stages might be fuzzy around the edges, things are clearer in the middle.

By way of illustration, the predicate “tall” is somewhat vague. After all, who can say what the precise cutoff is between being tall and not being tall? Is the cutoff between precisely at 6’? 6’5”? Where is it? The answer – if there is one – is hard to give.[20]

But whereas we may feel uncomfortable stating a cutoff, most of us would not hesitate to say that Perter Dinklage (4’4”) is not tall, but Shaquille O’Neal (7’1”) is. If this is the case, then it tends to show that we don’t have to have a perfectly identifiable cutoff in order to recognize clear-cut cases.

To apply this, we simply get comfortable with the notion that even though I can’t say for sure when my dad developed full-blown early-stage Alzheimer’s, we are comfortable saying that by 2008, he was in middle stage. He was clearly in middle stage. Similarly, by 2016, he was clearly in late stage. And I can say this even though I have no idea when he transitioned from middle to late stage.

Notes:

[1] See n.n., “Stages of Alzheimer’s,” Alzheimer’s Association, n.d., <https://www.alz.org/alzheimers-dementia/stages>.

[2] Robert Berkow, et al., eds., “Delirium and Dementia,” The Merck Manual of Medical Information, Home Ed., New York: Pocket Books, 1997, p. 366.

[3] Technically, it should probably be the AsDL, but that looks and sounds awkward. Let’s never speak of it again.

[4] “The Stages of Alzheimer’s,” Alzheimer’s Association, loc. cit.

[5] Just to give it a name, let’s call that “liminal uncertainty,” or LU for short.

[6] inally, Dr. Barry Reisberg of New York University Medical School’s Alzheimer’s Disease Center for Cognitive Neurology, along with and Emile Franssen. They called their stages: “Normal,” “Normal Aged Forgetfulness” (a concept that seems to me to be reminiscent of V. A. Kral’s “benign senescence”), “Mild Cognitive Impairment,” “Mild Alzheimer’s Disease,” “Moderate Alzheimer’s Disease,” “Moderately Severe Alzheimer’s Disease,” and “Severe Alzheimer’s Disease.” See “Clinical Stages of Alzheimer’s Disease,” An Atlas of Alzheimer’s Disease, Mony de Leon, ed., Encyclopedia of Visual Medicine Series, New York: Parthenon, 1999, passim.

[7] See “What Are the Seven Stages of Alzheimer’s Disease?” Alzheimers.net, Jul 8, 2018, <https://www.alzheimers.net/stages-of-alzheimers-disease/>.

[8] See Angela Stringfellow, “The 7 Stages of Alzheimer’s Disease: What to Expect From Preclinical Alzheimer’s Disease to End-Stage Alzheimer’s,” CaregiverHomes, Oct. 12, 2017, <https://blog.caregiverhomes.com/the-7-stages-of-alzheimers>.

[9] True, in some presentations, “Stage 1” is limited to adults. So, Carrie Hill, writing for VeryWellHealth in an article titled “The 7 Stages and Symptoms of Alzheimer’s Disease,” states that Stage 1 describes “a normally functioning adult,” Jun 26, 2018, <https://www.verywellhealth.com/alzheimers-symptoms-98576>. Firstly, even so, assuming that we reckon adulthood from legal emancipation – let’s say between the ages of 18 and 21 – that leaves quite a spread. Do we really want to say that a normal, healthy 22-year-old college graduate has “Stage 1 Alzheimer’s”? But, secondly, concerning “Stage I: Normal,” Barry Reisberg and Emile Franssen – both credited with the initial and presumably authoritative articulation of the sevenfold taxonomy – write: “At any age, persons may potentially be free of objective or subjective symptoms and functional decline and also free of associated behavioral mood changes. We call these mentally health persons at any age, stage 1, or normal.” (Italics supplied.) From Reisberg and Franssen, op. cit., p. 11.

[10] “Mild Cognitive Impairment (MCI),” Mayo Clinic, Aug. 23, 2018, <https://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/symptoms-causes/syc-20354578>.

[11] “Mild Cognitive Impairment,” Memory and Aging Center: Weill Institute for Neurosciences, Univ. of Cal. – San Francisco, n.d., <https://memory.ucsf.edu/mild-cognitive-impairment>.

[12] “What Are the Seven Stages of Alzheimer’s Disease?” Alzheimers.net, op. cit.

[13] “Frequently Asked Questions : Prodromal Alzheimer’s,” Glasgow Memory Clinic, n.d., <http://glasgowmemoryclinic.com/faqs/prodromal-alzheimers/>.

[14] This, by itself, by no means implies that there are no such things as “souls” in the more conventional, spiritual/religious sense. But, such a discussion lies well beyond the scope of the present work. I simply wish to make it clear that this portion of the text does not depend in any way on spiritual or religious conceptions of “soul”/psyche. There is a kind of neutral sense, as I state in the main text.

[15] For the bird’s-eye view, see S. Marc Cohen, “Aristotle on the Soul,” Univ. of Washington, Sept. 23, 2016, <https://faculty.washington.edu/smcohen/320/psyche.htm>.

[16] See “What Are the Stages of Alzheimer’s Disease?,” Healthline, n.d., <https://www.healthline.com/health/stages-progression-alzheimers>.

[17] Staff writers, “Alzheimer’s Stages: How the Disease Progresses,” Mayo Clinic, Dec. 12, 2018, <https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/in-depth/alzheimers-stages/art-20048448>. The author or authors go on to define “[d]ementia” as “a term used to describe a group of symptoms that affect intellectual and social abilities severely enough to interfere with daily function,” ibid.

[18] I am certainly not saying that the Mayo Clinic staff formulated in reply to my criticism!

[19] “Stages of Alzheimer’s,” Alzheimer’s Association, n.d., <https://www.alz.org/alzheimers-dementia/stages>.

[20] It may even be that there is a certain irreducible relativity. Maybe we shouldn’t speak solely of being “tall” – period – but, rather, being “tall for a [blank],” where the [blank] stands in for some role or profession. So, maybe we should not say that so-and-so is either “not tall” or is “tall” – full stop. For maybe we should only say that he or she is “not tall for a basketball player” or is “tall for a lawyer,” etc. But let’s just forget about this, presently.

How to Boost Memory & Possibly Avoid Alzheimer’s Dementia

Depiction of a 'Mind Palace'

Insofar as Alzheimer’s Disease erodes the cognitive and mental powers, and insofar as memory is one of these powers, it stands to reason that boosting your memory might serve you well as a dementia-preventive. Let’s go with that! In any case, one interesting and (I think) neglected area in discussions of dementia is memory development.

There are numerous memory-enhancing techniques including the adoption (or construction) of mnemonic devices, the ceasing of over over-reliance upon artificial memory aids, the creation of a so-called “memory palace” (or “mind palace”), and the use of the “major system. Let’s take a brief look at each of these.

Disclaimers

Okay, first of all, I am not a doctor. In fact, I have no medical training whatsoever. So, I am definitely not claiming that memory-boosting techniques are literally a prophylaxis against dementia. There is no scientific research about this either way, as far as I am aware. Rather, the simple and intuitive idea is that forging stronger neural connections and strengthening memory might be an effective – and unexplored – method for stacking the odds in your (and my!) favor. To put it crassly, the better your memory works, the longer it might take to erode.[1]

Second, though, I am by no means an expert on memory, mnemonics, neuroscience, or any similar field. The information and suggestions herein are merely the overflow of my own research. I am interested in avoiding my dad’s end. (If you’re interested in hearing about my personal dealings with Alzheimer’s vis-à-vis my dad, read Jim’s Story, HERE.)

The bottom line, as always, is that my content is presented as-is, with no guarantees or warranties of any kind. It’s just me, chronicling my own investigations and sharing with you, in case you might be interested in picking up where I leave off. (Or, in retracing my steps. Whatever.)

What Put Me onto This? Our Slipping Memories

One day the thought popped into my head that collectively (as a “culture,” whatever that word really means) we might be thought to be suffering from a kind of “mass Alzheimer’s.”

Here’s what I mean. On a daily basis it appears that we use our own brains for fewer and fewer daily tasks.

Generally, we don’t add up our bill at the super market. We let the checker do that. Even if we’re the checker, as a rule, we don’t tally the bill mentally – or even by hand. We rely on a computer to do that.

Now this is just one task. And, admittedly, computers didn’t start this “problem” (if it is a problem). Before smartphones and tablets, we had calculators. I’m not sure if anyone ever carted an abacus around a grocery store. But if they did, then calculators didn’t start the trouble, either.

But what worries me isn’t a grocery bill. It’s the fact that many of us seem to be ceding more and more mental territory over to the machines.

Calendars? Most of mine is on my phone. Phone numbers? How many of those do you actually know by heart?

In other words, it’s conceivable that these electronic assistants are, after all, crutches. It’s possible that they impede our even retard our natural capacities to remember.

The other day I was trying to recollect the name of a movie. In itself, the incident was as meaningless as the piece of information I was trying to recall. But, my first impulse was to just “Google” it.

But I don’t have to remember anything; if Google can remember things “for me”; then… isn’t my own memory starting to atrophy?

Anyway, for what it is worth to you, that was my thinking process. Take it or leave it.

One of my own takeaways is that it’s probably wise to scale back my reliance on artificial memory aids. Instead, I want to make it my goal to try to develop a rich “inner” structure of memory support.

This, in turn, got me enthusiastic for the prospect of revisiting a few memory techniques with which I have been cursorily familiar for several years. I thought that I would just sketch them out – for my benefit (and for that of any interested readers).

A Bit for History Buffs

Many of the tried and true memory systems are certainly not recent inventions. They go back hundreds of years – if not millennia.

The frustrating thing is that a lot of the details have been lost concerning how these systems worked. Here are some notable exceptions.

The 4th-c. B.C. Greek philosopher Aristotle wrote a few passages “On Memory and Reminiscence,” which were included as part of a proto-scientific biological work called a “Brief Treatise on Nature.”[2]

Another important early text is titled, in Latin, Rhetorica ad Herennium (circa 80-90 B.C.). This opaque phrase simply refers to the fact that it is a treatise on rhetoric written specifically for a now-unknown person named “Herrenius.” (Read some of the relevant passages, translated in English, online HERE. It’s only about fifteen paragraphs in the English translation.)

If it weren’t for the spectacular stories told to illustrate the prodigious feats of memory that were supposedly possible based on ancient memory techniques, these scattered writing might be considered nothing more than curious historical footnotes. But consider the case of one Simonides of Ceos.

According to the tale, Simonides was invited to a great feast at which there were dozens of other attendees. (Unfortunately for this article on the power of memory, I have forgotten the exact number of other guests – which is probably unknown in any case.) Let’s say that there were 100 people present.

At some point during the feast, Simonides was summoned out of the dining hall. No sooner had he left than the building collapsed with a great crash. Not only were the occupants killed, they were mangled beyond all recognition.

Bystanders, investigators, and would-be rescuers fretted over the seemingly futile task of identifying the victims. But, so the story continues, Simonides was able to recall each guest and his or her place at the great feasting tables. He did this through a fantastic mastery of the “method of places” (or loci), which was one facet of the memory skills that have faded into obscurity.

Going on, the famous Roman statesman and philosopher Cicero wrote about some memory techniques in a book called “On the Orator.”[3] We also have a few comments from the rhetorician Quintilian in his “Institutes of Public Speaking.”[4]

Truthfully, however, most of these works consist of little more than roundabout references to the Ars memoriæ (the “Art of Memory”). None of these surviving works is anything like a thoroughgoing teaching manual. The references mostly assume that readers are fully familiar with the methods under discussion.

This means that interested persons today need to do a bit of sleuthing – and depend upon the reconstructions of various scholars.

However, these investigators do have a bit of secondary literature to go on.

For example, such techniques (or something similar) were apparently known to the Medievals. Well-known Catholics like Albert the Great and his protégé, Thomas Aquinas, incorporated memory methods into their approach to learning and theology, a blend that has come to be termed scholasticism.

Or again, the relevant ancient memory techniques were apparently resurrected around the 16th century, during the Renaissance, by such authors as Johannes Romberch[5] and Giordano Bruno.[6] Memory feats were again taken to high, Simonides-like levels by people like the aforementioned Bruno, as well as thinkers such as Athanasius Kircher and Matteo Ricci (among others).

In the 17th century, an obscure English writer named Henry Herdson published a few short texts on the subject, the most important of which was Ars Memoriæ: The Art of Memory Made Plaine (sic).[7]

Closer to our time,  the late 20th-c. British historian Frances Amelia Yates examined and then repackaged a lot of the available information in her important The Art of Memory.[8]

Within two years of the publication of Yate’s research, the important 20th-century neuropsychologist Alexander Luria wrote up his case study on Solomon Shereshevsky, a supposedly untutored Russian businessman who had an intuitive mastery of various “imaginal” memory strategies.[9]

Shereshevsky was an exceptional and intriguing figure. But as far as can be determined, it wasn’t as if he had been privy to some ancient learning that is unavailable to the rest of us. He just seemed to devise various memorization strategies himself and was able to implement them with an uncanny ease.

More recently, some of these ancient techniques – or our modern approximations – have been the subject of a best-selling book, Moonwalking With Einstein, by New England-based journalist Joshua Foer.[10]

What Are the Actual Techniques?

If you read the foregoing – and didn’t just skip down – you might be saying: “That’s all well and good. But what is really going on?”

And, more practically speaking, how can a person boost his or her memory? In other posts, I give recommendations for how various herbs, nutrients, physical exercises, and vitamins can help to enhance and support brain functions. (Check those out HERE, HERE, HERE, HERE, and HERE.)

But there are additional mental activities and exercises that can augment – or at least “work out” – our innate abilities to store and recall pieces of information.  Here are some of those techniques – briefly summarized – along with a few additional tips.[11]

Don’t (over-)rely on memory aids.

This is the first and, given what I wrote earlier, possibly the most obvious. If our memories are being deteriorated by underuse, then the most apparent starting place will simply be to start using it. You don’t need to move straight into memorizing a list of 100 guests at a dinner party. Start with the ten items that you need to grab from the market or the phone number for the doctor’s office.

Use the ‘major system.’

But you have trouble remembering numbers, you say? Well, never fear, for there are one or two “tricks” up a mnemonist’s sleeves. The “Major System” is a sort of phonetic numbering tactic. The system entails letting letters stand in for numerals. The idea is that if you can turn numbers into words, you can recall them more readily.

There are several variants floating around, but the one that I was exposed to goes like this.

  • 0 stands in for “S,” “TS,” “Z”
  • 1 stand in for “D” and “T”
  • 2 stands in for “N”
  • 3 stands in for “M”
  • 4 stands in for “R”
  • 5 stands in for “L”
  • 6 stands in for “CH,” “G” (soft), “J,” and “SH”
  • 7 stands in for “G” (hard) or “K”
  • 8 stands in for “F” and “V”
  • 9 stands in for “B” and “P”

Consider a number, like 555-1212. Suppose that someone gives you this as the name of an Alzheimer’s specialist that you should contact. The idea of the major system is that you can bring in your letter substitutions. So the “5s” would become “Ls”: 555 = LLL. Then the “1212” becomes either: “DNDN” or “TNTN” (or some variation: such as “DNTN” or “TNDN”).

You then create a memorable word or phrase by inserting vowels in between the consonant letters. So, “LLL” might become “aLLeLuia” and “TNTN” might become “TiNTiN.” And you might imagine the Belgian cartoonist’s Tintin character exclaiming “Alleluia!” or singing Handel’s famed chorus.[12]

Create Mnemonics for Yourself

The word “mnemonic” has come to mean, basically, memory aid. It comes to us from the Greek word “mnemonikos[,] ‘of or pertaining to memory’.”[13]

Of course, this method is as varied as it is tried and true. What school child hasn’t had the experience of learning the names of the Great Lakes by memorizing the acronym “HOMES” – representing Lakes Huron, Ontario, Michigan, Eerie, and Superior?

The lesson? You can give your memory an assist by linking longer lists to something shorter and more readily remembered. So, the lakes might be harder to recall by themselves. But when we “hook” each of their names to a letter in a word like “homes,” we give ourselves a kind of memory “handle.”

There is another way that this can be made to work for you. To get at it, consider something called the “Baker-baker Paradox.”

Simply stated: “Remembering that a man’s name is Baker is harder than remembering that he is a baker. [Oxford-based experimental psychologist] Gillian Cohen called this the ‘Baker-baker paradox.’ The exact same word, ‘baker,’ is hard to remember as a name, but easy to remember as a profession.”[14]

As author Joshua Foer put it in his “TED Talk,”[15] the key to mining memory-boosting tips from this psychological principle is as simple as “turning big ‘B’ Bakers into little ‘b’ bakers.”[16]

Foer illustrates this by suggesting that if you have to remember that someone’s last name is “Baker,” you can improve your chances of doing so by picturing the person decked out in the accoutrements of the baking profession – baker’s hat, rolling pin, bags of flour, etc.

I was once introduced to a somewhat stout bank teller by the name of “Joe.” With no disrespect, I immediately thought of “sloppy Joe” and visualized him wearing a messy apron. Months later when I had the occasion to return to that branch (which was otherwise off the beaten path for me), I saw his face, which triggered the image, and I was able to greet him by name – which surprised him , frankly.

Build yourself a mind palace.

The importance of this technique is matched only by its complexity and nuance. The previously mentioned Giordano Bruno (among others) spent an entire book teasing out some of the subtleties. In this small space I can only scratch the surface.

The basic idea is the combination of mnemonic devices and the creation of a mental construct variously called a “memory palace” or a “mind palace.”

Fans of British television may already possess a passing familiarity with this method, as it features in the BBC’s Sherlock, with Benedict Cumberbatch playing the timeless Sherlock Holmes and Martin Freeman ready at hand as his trusty friend and partner, Dr. John Watson. Additionally, mind palaces assume great importance in shows involving the self-proclaimed “psychological mentalist” Derren Brown.[17]

The mind palace works roughly like this. First you visualize a sprawling space. I think that the idea is to conceptualize a location with which you are intimately familiar. So, you might use your house, for example. Let’s say that you do.

Next, you take a list of things that you need to remember, and you make the list more readily memorizable by “coding” the objects, names, or numbers (or whatever it is you need to remember) into vivid mental pictures. You then “place” these images around your well-known location.[18]

Now, I am no expert on this, but my impression is that you would do something like the following. Suppose you have to purchase butter, eggs, potatoes, milk, and flour from the grocery store. You imagine a cow holding a bouquet of flowers to encode the “milk and flour.” Perhaps you mentally position this cow in the entryway of your house. You proceed into the interior or the home, let’s say ending up the living room. And you picture a flaming potato in your fireplace. Walking a little farther, you glance into the kitchen. Maybe you code the “eggs and butter” by picturing a chicken sliding around on butter smeared on the tiled floor.

What you end up with is your list of five grocery items, transformed into memorable images, and strewn around your house in a particular order.

The utility of the loud and crazy images is that they make recall easier than it would be if you were trying to remember the boring objects by themselves. And the point of placing them around a physical location is to keep track of what you have to remember. By mentally “walking through” your image of the house, you will “notice” the objects deposited in various places. You won’t forget anything, according to adherents of this method, because you will encounter each item as you proceed through the space. This is why the space ought to be a familiar one – like your own home.

Summary

4 Quick Memory-Boosting Tactics

  1. Try not to rely on calculators, smartphones, or Google. Use your own brain!
  2. Convert numerals into words with the “Major System.”
  3. Transform lists into words and Bakers into bakers (see above!) with mnemonics.
  4. Construct a “memory palace” and place items inside of it using the “method of places.”

For the details, refer to the main text. Happy remembering!

Further Reading

10 Things to Do Now to Reduce Your Alzheimer’s Risk Later in Life

How Does a Person Actually Die From Alzheimer’s Disease?

75+ Questions to Ask a Doctor About an Alzheimer’s Diagnosis

Notes:

[1] Is this true? I don’t know. But it sounds plausible to me. And, frankly, using these techniques has a number of ancillary benefits, anyway. I suppose what I’m saying is that there’s little to no downside to this – unless, of course, you don’t want to invest the time. Which is a totally fair point, and completely up to you.

[2] In Greek, Peri Psuchēs: Peri Mnēmēs kai Anamnēseōs; in Latin Parva Naturalia: De Memoria et Reminiscentia.

[3] De Oratore, 55 B.C.

[4] Institutio Oratoria (12 vols.), circa A.D. 95.

[5] See his Congestorium artificiose memoriæ (roughly translated as “Tales Concerning the Kinds of Memory”), Venice: M. Sessa, 1520; 1533.

[6] See De umbris idearum (“On the Shadows of Ideas”), Paris: Ægidium Gorbinum, 1582; Ars Memoriæ (“The Art of Memory”), Paris: Ægidium Gillium, 1582; and Cantus Circæus (“Circe’s Song”), Paris: Ægidium Gillium, 1582.

[7] Henry Herdson, Ars Memoriæ: The Art of Memory Made Plaine, London: Gartrude Dawson, 1651.

[8] Chicago: Univ. of Chicago Press, 1966.

[9] See Alexander Luria, The Mind of a Mnemonist: A Little Book About a Vast Memory, New York: Basic Books, 1968.

[10] Joshua Foer, Moonwalking with Einstein: The Art and Science of Remembering Everything, New York: Penguin, 2011.

[11] I just concluded a section enumerating many scholarly tomes unpacking the Art of Memory

[12] I realize that it’s normally referred to as the “Hallelujah Chorus,” but this is arguably just a transliteration quibble and, well… you get the picture.

[13] Douglas Harper, “Mnemonic,” Online Etymology Dictionary, 2018, <https://www.etymonline.com/word/mnemonic>.

[14] Ira Hyman, “Large Mocha without a Name,” “Mental Mishaps” (blog), Psychology Today, Feb 24, 2010, <https://www.psychologytoday.com/us/blog/mental-mishaps/201002/large-mocha-without-name>.

[15] Joshua Foer, “Feats of Memory Anyone Can Do,” YouTube, May 10, 2012, <https://www.youtube.com/watch?v=U6PoUg7jXsA>.

[16] Ibid.

[17] For an entertaining illustration of which, see HERE.

[18] This is also sometimes called the “method of places.”

10 Things to Do Now to Reduce Your Alzheimer’s Risk Later

10 Things to Do Now to Reduce Your Alzheimer’s Risk Later in Life

A diagnosis of Alzheimer’s – or of another form of dementia – is a scary thing for a person and his or her family. It is literally lifechanging. We went through the rollercoaster of emotions when my dad, Jim, was diagnosed around 2008. (Read “Jim’s Story,” HERE.)

Much of this website is devoted to things that caretakers can do to better safeguard the home environment.[1] But you don’t want to neglect those things that you yourself can do to minimize the risk of developing Alzheimer’s in the first place. This will include basic tips like these: Get regular exercise; Drink purified water; Reduce your alcohol intake; Make sure you get your nutrients; Sit less; Turn off the TV; Boost your brain activity; Improve your memory; Supplement with herbs and spices; and Get adequate amounts of sleep.

Caveats

Despite researchers’ best efforts, Alzheimer’s Disease remains largely a mystery in many ways. This means that there are no agreed upon – let alone “guaranteed” – ways of avoiding or treating Alzheimer’s. And, presently, there is no cure. This means that, relatedly, there can be no definitive list of “things you can do” to avoid Alzheimer’s.

But this last fact by no means rules out the idea that, based upon our current state of knowledge, some lifestyles changes seem to hold out the promise of improving our odds. (It also gives me an incentive to try to stack the deck in my favor, health-wise. After all, I don’t want any disease; but I especially don’t want a disease about which little is known.) So, even though I am not a doctor and none of what is written in this post constitutes medical advice (for which, see your local healthcare professional), what is included is a bit of what I have done for myself. Even though these suggestions are speculative, there are some indications in the relevant literature that a few of these tips might be effective. Do what you will with the information; employ suggestions at your own risk.

Top Ten List

1. Exercise More

Regular exercise is routinely touted as valuable for health. Even if it’s not quite the fabled panacea, there is no denying the litany of positive benefits associated with it.

For example, exercise strengthens and tones muscles. It can therefore help you to feel – and look – better. This, in turn, can decrease your risk of certain illnesses (e.g., diabetes and heart disease).

But, getting into an exercise routine can also improve the health and vitality of your brain.

One doctor, Jonathan Graff-Radford, writing for the celebrated Mayo Clinic, explains: “Physical activity seems to help your brain not only by keeping the blood flowing but also by increasing chemicals that protect the brain.”[2]

An article published on the website of the prestigious Harvard Medical School stated that: “Regular exercise changes the brain in ways to improve memory and thinking skills…”.[3] This is partly because exercise has anti-inflammatory effects on various parts of the body and it also helps ensure that body internal body chemistry (including insulin and “growth factors”) are optimal.”[4]

Scientific American even published a tantalizing article that claimed exercise might be able to “clean up” the “hostile environments in the brains of Alzheimer’s mice, allowing new nerve cells …to enable cognitive improvements, such as [for] learning and memory.”[5]

Whether you bike, dance, walk, or weight lift, getting at least some exercise every day is repeatedly emphasized as a boon to your overall health.

2. Drink Filtered Water

Do you have any idea how much crud can potentially be in your tap water? Municipal water supplies are contaminated with many chemicals and other substances. These range from herbicides, pesticides and industrial byproducts, to metals like aluminum, lead, and mercury. There are even detectable levels of various microorganisms, pharmaceuticals, and other toxins – in the water that comes out of your faucet!

Numerous of these compounds have been linked to cancer, inflammation, and an assortment of other health problems. For much more detail on these, and related, water-contamination issues, see HERE.

While a definite causal mechanism for Alzheimer’s Disease still has not been pinned down, the condition is often characterized by brain degeneration, inflammation, and toxicity.

Could all the crap floating around in America’s water supplies be at least a contributing cause?

The fact that this seems to be a live possibility leads me to one practical conclusion: To raise the probability that I will escape my dad’s fate, I want to drink the cleanest water available. And my research (which again, is summarized HERE) leads me to think that this means I need to filter my own water.

So, get yourself a good quality filter. Keep it serviced. And stop imbibing chemical-laced tap water!

For my specific filter-related product recommendations, click HERE.

3. Reduce Alcohol Consumption

I’ll admit: This is a tough one for me. I do love a good whiskey. (Sometimes, I’ll even love a bad one.)

Alcohol, especially red wine, is associated with various health improvements. For example, it is reputed to reduce the risk of stroke and to improve general health.

On the other hand, some argue that the component bringing the actual benefits (resveratrol) may be better consumed through other sources, because of the potential dangers of alcohol.

For instance, alcohol can have adverse effects on many of the body’s parts, including the circulatory system and heart (from raising blood pressure to causing irregular heart rhythms) as well as the liver (including cirrhosis, “fatty” liver, and inflammation).

But, most pertinently, alcohol has links to brain problems, including – you guessed it – Alzheimer’s and other forms of dementia.

For a more in-depth discussion of the pros and cons of drinking alcohol, as well as for more related information, see my article, HERE.

Like so many other things in life (not to mention on the present list), perhaps the best advice is this: moderation. “Moderation,” of course, has to do with the avoidance of extremes – that of deficiency on the one hand and overindulgence on the other.[6]

4. Get Your Nutrients

Some observers suggest that Alzheimer’s Disease comes in different varieties. (For more on this intriguing idea, see HERE.)

Relevantly, one of the sub-varieties (“Type 2,” in the idiom of Dr. Dale Bredesen) is believed to be precipitated by nutrient deficiencies of one sort or other.

The basic notion is that our cognitive faculties – things like our abilities to remember and to think – depend on hormonal, nutritional, or other “trophic” support.

In my research, some vitamin deficiencies are possibly important to note.

Vitamin B12. For one thing, there is a bit of literature on the subject of B12 deficiency. B12, also known as cobalamin, plays an essential role ensuring the body’s health at a cellular level. B12 is especially important for blood cells as well as nerve cells. There is some dispute over whether a lack of B12 causes Alzheimer’s per se[7] or whether B12 deficiency is simply Alzheimer’s-like.[8] Honestly though, it’s good advice to keep up your levels of B12 regardless of which is the case.[9]

Vitamin D. Another notable entrant on this list has to be vitamin D. HERE I go more in depth on what vitamin D actually is and why it’s important. For the time being, let’s just say that the august Mayo Clinic has noticed that “people with very low levels of vitamin D …are more likely to develop Alzheimer’s disease and other forms of dementia” than are people whose vitamin-D levels are normal.[10]

Copper. Copper is a further substance that sometimes crops up in articles on possible links between dementia and nutrient deficiencies. A lack of copper might bring about the onset of Alzheimer’s Disease. Or so says one school of thought on the matter.[11] However, others maintain that copper actually precipitates Alzheimer’s![12] Although the jury’s still out on this issue, it seems reasonable to try to keep your copper intake to within the Food and Drug Administration’s so-called “recommended daily allowances.” Currently, this is supposedly 900 micrograms per day.

Since copper may end up in our bodies via the pipes that carry water into our homes, it may be advisable to invest in a good-quality filter. (For more on this, see the relevant section in this article, above. For specific water-purification recommendations, see HERE.)

Of course, at the most basic level, you want to ensure that you’re eating a balanced diet. Some nutritionists even speak of specialized diet plans such as those geared towards reducing inflammation. For more on dietary tweaks, click HERE, HERE, and HERE.

5. Boost Brain Activity

Earlier, I mentioned the importance of physical exercise for brain health. But, there are also such things as “brain exercises.” To put it slightly differently, there are any of a number of ways to build and strengthen neural connections, as well as to sharpen your reason, and bolster your memory. Improving memory is so important I’m giving it its own separate section, below. Presently, I’ll just sort of dash off a few quick tips for giving your gray matter a bit of a workout.

Do some puzzles or ‘brain teasers.’ Okay: admit it. This is the tip that you’ve been expecting. Many people have heard this one. A good way to keep your brain active is to do crossword (or other) puzzles. And it’s certainly worth considering. Solving (or attempting to solve) puzzles activate brain connections that may have been dormant for some time. In other words, they tax our brains. Besides crosswords, there are brain teasers, checkers and chess problems, logic puzzles, sudokus, and so on. There’s practically something for everyone. So, think about trying one of these the next time you reach for your television remote.

Get creative. Write a poem. Write in a journal. Draw a picture. (Or paint one.) Turn on a piece of music. Sing along – trying to memorize the words. Sculpt. Act in a play (and memorize those lines). Alternatively, go to your local art museum and make a study of some of the pieces.

Learn something new. This could be something large and involved – like a new language or a musical instrument – or it could be something smaller – like a memorizable passage from a book or a word-of-the-day. You could take an actual class, or just read a book. (But, maybe try to avoid watching courses on tv. For the reason, see further on.) Keep challenging your brain, the thinking goes, and you’ll keep building neuronal pathways. And that’s a good thing.

Rely less on artificial and ‘external’ helps. What do I mean? Well, how much change are you owed as giving the cashier a $20 bill on a total of $17.23? Don’t just do nothing and assume that she knows the answer (or, more likely, that her register computer will tell her). Don’t turn immediately for your calculator (or, more likely, the “calc app” on your smartphone). Instead, try to work it out in your head.  (Okay… maybe you’re allowed a pencil and paper.) Scary, right? I realize. But think of it this way: you’re not being graded! Even if you get the answer wrong, at least you gave your brain a mini workout. And we’re surrounded with similar opportunities.

6. Work on Your Memory

One interesting and (I think) neglected area is memory development. This is in addition to giving your brain nutritional support as well as a “workout.” (For more on these, see the relevant sections, above.)

It seems that every day, we rely more and more heavily on cell phones and other electronic devices as memory aids. Part of our reliance pertains to maintenance of our daily calendars and schedules. And phone numbers? Who knows those any longer?!

But of late this over-reliance seems to have extended even to basic facts – which we can have told to us by the virtual voices of Alexa, Google Assistant, Siri, etc.

This might appear to be a great help. And, there’s no denying the “convenience” of it. However, it is possible that our dependence on these sorts of artificial helps has a negative impact on our natural capacity to remember things. So, here’s one quick suggestion that I have been taking to heart, lately.

Don’t (over-)rely on memory aids. If you have a list of things to purchase from the store, try to remember it. Of course, you should write it down – both as a backup and as a means of memorizing the list. But don’t be so quick to turn to the list for that next item. Put a little effort into trying to bring it to mind without any outside help. Make a game out of it.

Not scoring so well in this game? Take heart! For, believe it or not, there are ways of enhancing our memories.

(For more detailed explanations of these various techniques, see my companion article: “How to Boost Memory & Possibly Avoid Alzheimer’s.”)

Use the ‘major system.’ This system uses letter combinations as an assist to remembering numbers. To start with, you actually have to memorize the substitution list. (Sorry!) But after you have the short list down, it becomes a lot easier. It’s beyond the scope of the present article to explain the workings of the system. (For that stuff, click HERE!) Suffice it to say that this fairly straightforward mnemonic allows for the memorization of things like birthdates, social-security numbers, telephone numbers and the like. Impress your friends! But, more importantly, enhance your memory.

Build yourself a mind palace. The precise goings on are too nuanced to expound upon, here. At present, I will simply note that there are memory procedures involving the creation of mnemonic devices along with the construction (within the mind) of something termed a “memory palace”[13] – popularized on such television shows as the BBC’s Sherlock (airing in four seasons from 2010 to 2017 and starring Benedict Cumberbatch and Martin Freeman) as well as figuring in several performances by the British “mentalist” Derren Brown.[14]

While there is no word (that I have seen) regarding whether these techniques shield their user from dementias, as I have stated elsewhere, my concern is just stacking the odds in my favor. And, my guess is that it’s better to have a robust and healthy memory than, well… not.

Again, for the more detailed discussion of these memory-building techniques, see HERE.

7. Add Some Spice to Your Life

We have already discussed the fact that some vitamin (and other) supplements can usefully augment your diet, thus (possibly) stacking the odds of avoiding dementia more in your favor. But it turns out that some of the ingredients on your kitchen spice rack might actually reduce some of your Alzheimer risks as well.

I have also touched upon some of these elsewhere. (So check that out, HERE.) Suffice it to say, here, that several everyday seasonings also are reputed to have some potent health effects.

Here are just a few examples.

Cinnamon. Take cinnamon, for instance. According to an article just published in the academic journal Pharmacological Research, “[c]innamon …[is] a promising prospect towards Alzheimer’s disease.”[15] “[T]wo compounds found in cinnamon – cinnamaldehyde and epicatechin – are showing some promise in the effort to fight the disease. …[T]he compounds have been shown to prevent the development of the filamentous ‘tangles’ found in the brain cells that characterize Alzheimer’s.”[16]

Turmeric. One study suggests that turmeric (curcumin) may reduce Alzheimer’s-related brain inflammation and, consequently, improve patient’s memory. On the flip side, taking it before onset might stave off the Alzheimer’s Disease (AD). Here’s an excerpt from the article’s abstract. “Curcumin …has a potential role in the prevention and treatment of AD. Curcumin as an …anti-inflammatory …improves the cognitive functions in patients with AD. A growing body of evidence indicates that oxidative stress, free radicals, beta amyloid, cerebral deregulation caused by bio-metal toxicity and abnormal inflammatory reactions contribute to the key event in Alzheimer’s disease pathology. Due to various effects of curcumin, such as decreased Beta-amyloid plaques, delayed degradation of neurons, metal-chelation, anti-inflammatory, antioxidant and decreased microglia formation, the overall memory in patients with AD has improved.”[17]

Ginger. I should also mention ginger. Though, admittedly, in this case research suggests that ginger is useful not so much for Alzheimer’s prevention as for symptom management. The idea is that “traditional Chinese medicinal ginger root extract (GRE)” might help “to prevent behavioral dysfunction in the Alzheimer disease…”.[18]

8. Sit Less (and Stand More)

According to a scholarly article published in 2015: “Prolonged sedentary time was …associated with deleterious health outcomes regardless of physical activity.”[19] Got that? Regardless of physical activity!

That means that if you sit a lot – and “more than half of the average person’s waking hours are spent sitting”[20] doing one activity of other – then you are increasing your risk for numerous conditions and diseases.

I’ve gone into this elsewhere. (For more, see HERE.) But, in general terms, “too much sitting …increases the risk of heart disease, diabetes and premature death.”[21]

And wouldn’t you know it? Sitting is also bad for the brain, specifically. Too much sitting can cause a “[t]hinning in brain regions [that are] important for memory…”.[22]

One study suggested to the writers at Medical News Today that the effects of a sedentary lifestyle were so pronounced as to raise a person’s level of risk to that which he or she would have if there were a genetic predisposition. Citing a 2017 article in the Journal of Alzheimer’s Disease,[23] one reporter observed that a “lack of exercise” – typical of people who sit all day long – “may be …as risky for dementia development …[as is] carrying the APOE e4 gene,”[24] for more on which gene, see HERE and HERE. To put some numbers to it, we’re talking in the neighborhood of three to twelve times higher risk.

That’s a huge and significant increase. So, get off your duff!

Stand More. A simple “fix” for sitting too much is, well… standing more often. There are a number of ways to do this, including getting standing desks for work. But, straightforwardly, just try to take every opportunity that you have to be a little more active. For some ideas to get you going – both literally and metaphorically – see HERE.

9. Turn off the Television

You might be thinking, “Some kinds of sitting are arguably worse than other others.” And this is doubtless true.

For instance, you can sit and work a crossword puzzle or read a Shakespearean sonnet. On the other hand, you could sit and “binge watch” your latest guilty pleasure on Netflix.

It turns out, then, not so much that extended sitting can be made better, but that its negative effects can be compounded with the introduction of television.

Indeed, the culprit, here, isn’t just “television” (full stop). It’s any related form of electronic-video viewing.

According to a 2015 article in America Magazine: “[T]he more TV you watch, the more likely you are to get Alzheimer’s disease.”[25]

This conclusion was based on a twenty-five-year study carried out by the San Francisco-based Northern California Institute for Research and Education. Commenting on the same research, one Washington Post writer explained that “too much TV might damage your brain and also raise the risk of developing Alzheimer’s disease.”[26]

In fact, a link between dementia and television had been suggested nearly fifteen years earlier.

In 2001, a Dr. Robert Friedland and his team declared that tv viewing was potentially deleterious to brain and cognitive health.[27] In their findings, watching television was highly correlated with Alzheimer’s. To put it another way, those who developed Alzheimer’s later in life had been observed to have been (or reported having been) “heavy” tv viewers.[28]

I go into greater depth on this, HERE. Suffice it to say that you might want to consider turning off – or, at least limiting your time in front of – the tube. (And I’ll certainly be considering the same thing!)

10. Relax – and Get Your Sleep

Now that you’re all good and worked up over your risk of developing Alzheimer’s, just try to settle down. What’s the saying? Worrying doesn’t add any days to your life. In fact, it might even subtract a few of them. So, cool it.

Seriously, though, this is important. I have elsewhere written about the necessity of getting optimal (or at least adequate) amounts of sleep. (It’s so crucial, it has two articles – and counting. Get started HERE and HERE.)

But a corollary of this advice is that we all (you and me both) need to stop worrying so much.

One article on the popular WebMD website relates that high levels of “…stress” might predispose us “for the kind of thinking difficulties that can lead to Alzheimer’s disease…”.[29]

The Mayo Clinic explains that stress prompts our bodies to release the hormone cortisol. In turn, chronically high cortisol levels can precipitate all sorts of health problems, including: emotional difficulties (e.g., anxiety and depression) as well as physical troubles. These latter can come in the form of so-called “stress” headaches, stomach troubles, and – yes – “[m]emory and concentration impairment.”[30]

Stress is also known to disrupt sleep. And this lack of proper rest and restoration can further increase stress – as well as put us at greater risk for Alzheimer’s.

Here are some things to try to minimize (or deal with) the stressors in your life.

Avoid drugs. This variously sounds absurd and obvious. But as I am reading over some of the things that can cause stress, what appears on the list? We’re talking about alcohol (which I addressed above), caffeine, cigarettes and nicotine, and so on. (I’m tempted to add sugar to that list. Ahem.) It sometimes seems that nothing good comes from these except addiction. Of course, we often hear platitudes like “all things in moderation.” (I even used it myself, above, regarding that chimerical beast, “moderate drinking.”) And if you do really have the ability to be moderate then… good for you! Sincerely! For the rest of us, maybe we should just lay off (as best we can). (Oh, my precious whiskey…)

Exercise. This stress-reduction list has a lot of similarities to the present article, n’est-ce pas? Coincidence? So, get out and move around a little – or a lot. It can do your body a lot of good just to go for a walk. Jog or run if you can manage. Do some yoga. Learn some breathing techniques. Lift weights. Cycle. You get the idea. Just do something.

Seek counseling. This may or may not require the hiring of a professional (and licensed) therapist of one kind or other. It may be as simple as just having good friends to lean on. Alternatively, it might necessitate engaging a “life coach,” personal assistant, or someone who can help make your daily tasks more controllable, predictable, and organized. Time management is a key, here.

Get more sleep! But this can be difficult (or practically impossible) when you’re already stressed out. It begins a proverbial vicious cycle. What can be done?

Well, here are a few herbs (and other things) that can take the edge off enough to help you get those Zs.

I’m focused on things that are, according to my untutored reading, not as habit-forming as alcohol (or even some of the prescription or OTC concoctions that people go in for these days).

My top herbal picks would include the following:

  • Hops (Humulus lupulus).
  • Lemon Balm (Melissa officinalis).
  • Passion Flower (Passiflora incarnata).
  • Valerian (Valerian officinalis).

For the a non-herbal sleep assist, it’s hard to do better than the amino acid:

  • L-Tryptophan.

For more in-depth information on these supplements – and for several other recommendations (e.g., GABA and melatonin) – click HERE.

A final suggestion is to regulate your light and sunlight exposure. Here’s what I mean. It can be extremely beneficial to get some sunlight during the day. For instance, natural light helps your body produce vitamin D naturally. (For more on this, see above as well as HERE and HERE.)

Equally and oppositely, limiting light exposure at night can be vital for your ability to sleep. For most people (who don’t work nights), limiting sunlight isn’t a problem during their scheduled sleeping period. But, here, it is essential to reduce your exposure to artificial lights – including electronic displays. (Read additional tips HERE.)

Summary

10 Things You Can Do to Lessen Your Alzheimer’s Risk:

  1. Exercise
  2. Drink Purified Water
  3. Cut Back on Alcohol
  4. Eat Well & Take Your Vitamins
  5. Give Your Brain a Workout
  6. Enhance Your Memory
  7. Reach for Your Kitchen Spices
  8. Sit Less/Stand More
  9. Watch Less TV
  10. Get Enough Rest

Notes:

[1] See the five-part guide to Alzheimer’s-proofing a home: Part 1 – Master ListPart 2 – Senior SafetyPart 3 – Alzheimer’s TipsPart 4 – Kitchens & BathsPart 5 – Indoors & Outdoors..

[2] Jonathan Graff-Radford, “Alzheimer’s Disease: Can Exercise Prevent Memory Loss?” Mayo Clinic, <https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/expert-answers/alzheimers-disease/faq-20057881>.

[3] Heidi Godman, “Regular Exercise Changes the Brain to Improve Memory, Thinking Skills,” Harvard Medical School, Apr. 9, 2014; updated Apr. 5, 2018, <https://www.health.harvard.edu/blog/regular-exercise-changes-brain-improve-memory-thinking-skills-201404097110>.

[4] “[G]rowth factors …[are] chemicals in the brain that affect the health of brain cells, the growth of new blood vessels in the brain, and even the abundance and survival of new brain cells.” Ibid.

[5] Jonathan Grinstein, “How Exercise Might ‘Clean’ the Alzheimer’s Brain: Hints at Potential Treatments for Age-Related Dementia and Memory Loss,” Scientific American, Oct. 16, 2018, <https://www.scientificamerican.com/article/how-exercise-might-clean-the-alzheimers-brain1/>.

[6] It’s something like an application of Aristotle’s famous “golden mean.” A commonly cited example is that of courage that, properly construed is “midway” (so to speak) between cowardice and recklessness abandon.

[7] But see Jennifer Warner, “Vitamin B12 Linked to Lower Alzheimer’s Risk,” WebMD, Oct. 18, 2010, <https://www.webmd.com/alzheimers/news/20101018/vitamin-b12-linked-to-lower-alzheimers-risk>.

[8] See, e.g., “What’s Causing Your Memory Loss? It’s Not Necessarily Alzheimer’s,” HelpGuide, n.d., <https://www.helpguide.org/harvard/whats-causing-your-memory-loss.htm>.

[9] For more reading, see A. Osimani, A. Berger, J. Friedman, B. Porat-Katz, and J. Abarbanel, “Neuropsychology of Vitamin B12 Deficiency in Elderly Dementia Patients and Control Subjects,” Journal of Geriatric Psychiatry and Neurology, vol. 18, no. 1, Mar. 2005, pp. 33-8, <https://www.ncbi.nlm.nih.gov/pubmed/15681626>.

[10] Jonathan Graff-Radford, “Can Taking Vitamin D Supplements or Spending More Time in the Sun Help Prevent Alzheimer’s and Other Forms of Dementia?” Mayo Clinic, May 30, 2018, <https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/expert-answers/vitamin-d-alzheimers/faq-20111272>.

[11] See, for instance, J. Xu, S. Church, S. Patassini, P. Begley, H. Waldvogel, M. Curtis, R. Faull, R. Unwin, and G. Cooper, “Evidence for Widespread, Severe Brain Copper Deficiency in Alzheimer’s Dementia,” Metallomics, Aug 16, 2017, vol. 9, no. 8, pp. 1106-1119, <https://www.ncbi.nlm.nih.gov/pubmed/28654115> and L. Klevay, “Alzheimer’s Disease as Copper Deficiency,” Medical Hypotheses, vol. 70, no. 4, Oct. 24, 2007, pp. 802-807, <https://www.ncbi.nlm.nih.gov/pubmed/17928161>.

[12] For the Cliff’s Notes’s version, take a look at Andrew Weil, “Does Copper Lead to Alzheimer’s?” Dr. Weil (dot) com, Nov. 11, 2013, <https://www.drweil.com/health-wellness/health-centers/aging-gracefully/does-copper-lead-to-alzheimers/>.

[13] This is also sometimes called the method of places

[14] For an entertaining illustration of which, see HERE.

[15] “Various cinnamon species and their biologically active ingredients have renewed the interest towards the treatment of patients with mild-to-moderate A[lzheimer’s]D[isease] through the inhibition of tau protein aggregation and prevention of the formation and accumulation of amyloid-β peptides into the neurotoxic oligomeric inclusions, both of which are considered to be the AD trademarks.” according to S. Momtaz, S. Hassani, F. Khan, M. Ziaee, and M. Abdollahi, “Cinnamon, a Promising Prospect Towards Alzheimer’s Disease,” Pharmacological Research, vol. 130, Dec. 2017 (online); Apr. 2018 (in print), pp. 241-258, <https://www.ncbi.nlm.nih.gov/pubmed/29258915>.

[16] “Cinnamon Compound Has Potential Ability to Prevent Alzheimer’s,” Science Daily, May 23, 2013, <https://www.sciencedaily.com/releases/2013/05/130523143737.htm>; citing Roshni George, John Lew, and Donald Graves, “Interaction of Cinnamaldehyde and Epicatechin with Tau: Implications of Beneficial Effects in Modulating Alzheimer’s Disease Pathogenesis,” Charles Ramassamy, ed., Journal of Alzheimer’s Disease, vol. 36, no. 1, Jun. 2013, pp. 21-41, <https://www.j-alz.com/vol36-1>.

[17] Shrikant Mishra and Kalpana Palanivelu, “The Effect of Curcumin (Turmeric) on Alzheimer’s Disease: An Overview,” Annals of Indian Academy of Neurology, vol. 11, no. 1, Jan.-Mar. 2008, pp. 13-19, <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781139/>.

[18] G. Zeng, Z. Zhang, L. Lu, D. Xiao, S. Zong, and J. He, “Protective Effects of Ginger Root Extract on Alzheimer Disease-Induced Behavioral Dysfunction in Rats,” Rejuvenation Research, Apr. 2013, vol. 16, no. 2, pp. 124-33, <https://www.ncbi.nlm.nih.gov/pubmed/23374025>.

[19] Aviroop Biswas, Paul Oh, Guy Faulkner, Ravi Bajaj, Michael Silver, Marc Mitchell, David Alter, “Sedentary Time and Its Association With Risk for Disease Incidence, Mortality, and Hospitalization in Adults: A Systematic Review and Meta-Analysis,” Annals of Internal Medicine, vol. 162, no. 2, Jan. 20, 2015, pp. 123-132, <http://annals.org/aim/article-abstract/2091327/sedentary-time-its-association-risk-disease-incidence-mortality-hospitalization-adults>.

[20] Julie Corliss, “Too Much Sitting Linked to Heart Disease, Diabetes, Premature Death,” Harvard Heart Letter, Jan. 22, 2015, online at <https://www.health.harvard.edu/blog/much-sitting-linked-heart-disease-diabetes-premature-death-201501227618>.

[21] Leigh Hopper, “Sitting Is Bad for Your Brain – Not Just Your Metabolism or Heart,” Univ. of Cal. – Los Angeles, press release, Apr. 12, 2018, <https://eurekalert.org/pub_releases/2018-04/uoc–sib041118.php>. See, also, Laurie Tarkan, “The Connection Between Sitting and Diabetes,” On-Track Diabetes, Jul. 27, 2017, <https://www.ontrackdiabetes.com/get-fit/motivation/connection-between-sitting-diabetes> and Earl Ford and Carl Caspersen, “Sedentary Behaviour and Cardiovascular Disease: A Review of Prospective Studies,” International Journal of Epidemiology, vol. 41, no. 5, Oct. 2012, pp. 1338-1353, <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582407/>.

[22] Hopper, op. cit. Cf. Prabha Siddarth, Alison Burggren, Harris Eyre, Gary Small, and David Merrill, “Sedentary Behavior Associated With Reduced Medial Temporal Lobe Thickness in Middle-Aged and Older Adults,” PLoS ONE (Public Library of Science), vol. 13, no. 4, Apr. 12, 2018, <https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195549>.

[23] Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, and Jennifer Heisz, “Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study,” Journal of Alzheimer’s Disease, vol. 56, no. 1, Jan. 2017, pp. 297-303. Relatedly, it is also the case that the dementia sufferers tend to be more sedentary than comparable non-dementia individuals. See Y. Hartman, E. Karssemeijer, L. van Diepen, M. Rikkert, and D. Thijssen, “Dementia Patients Are More Sedentary and Less Physically Active than Age- and Sex-Matched Cognitively Healthy Older Adults,” Dementia and Geriatric Cognitive Disorders, vol. 46, nos. 1-2, Aug. 24, 2018, pp. 81-89, <https://www.ncbi.nlm.nih.gov/pubmed/30145584>.

[24] Honor Whiteman, “Sedentary Behavior Raises Dementia Risk as Much as Genetic Factors,” Medical News Today, Jan. 15, 2017, <https://www.medicalnewstoday.com/articles/315173.php>.

[25] Mark Pattison, “New Study Shows Link Between TV Viewing and Alzheimer’s,” America; via Catholic News Service, Jul. 31, 2015, <https://www.americamagazine.org/content/all-things/tv-viewing-linked-alzheimers>.

[26] Fredrick Kunkle, “Too Much TV Could Raise the Risk of Alzheimer’s, Study Suggests,” Washington Post, Jul. 20, 2015, <https://www.washingtonpost.com/local/social-issues/too-much-tv-can-raise-the-risk-of-alzheimers-new-study-suggests/2015/07/20/7dcdc4cc-2eea-11e5-97ae-30a30cca95d7_story.html>.

[27] See, e.g., Roger Highfield, “Scientists Hint at Link Between TV and Alzheimer’s,” Telegraph (British newspaper), Mar. 6, 2001, <https://www.telegraph.co.uk/news/health/1325216/Scientists-hint-at-link-between-TV-and-Alzheimers.html>.

[28] Cf. David Wilkes, “Can TV Lead to Alzheimer’s?” Daily Mail (British newspaper), n.d., <https://www.dailymail.co.uk/health/article-28720/Can-TV-lead-Alzheimers.html>.

[29] Tara Haelle, “Stress and Alzheimer’s-Linked Thinking Problems,” HealthDay via WedMD, Dec. 11, 2015, <https://www.webmd.com/alzheimers/news/20151211/stress-may-boost-risk-for-alzheimers-linked-thinking-problems>.

[30] Staff writers, “Chronic Stress Puts Your Health at Risk,” Mayo Clinic, Apr. 21, 2016, <https://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/stress/art-20046037>.

Is Alzheimer’s Disease a Terminal Illness?

This is actually a fairly tricky question. There are numerous considerations and nuances. For one thing, it depends on whether we’re using a rough definition of “terminal illness” (typical of everyday speech), or if we’re using a technical definition (as we might in insurance or medical contexts). Here’s the short answer.

There is no cure for Alzheimer’s. It is inarguably “terminal” in the sense that a person who is diagnosed with the disease will eventually die with it. Although it certainly diminishes longevity and negatively impacts quality of life, Alzheimer’s will probably not result in immanent death for people who are in its early stages. However, by the time that an individual is in its advanced stages, life expectancy may be as little as one to two years. Thus, late-stage Alzheimer’s is often “terminal” in the technical sense as well.

What Is a ‘Terminal Illness’?

A General Definition

In general, if you have a “terminal illness,” then you have an illness that is expected to end with your death. Intuitively, if a disease is expected to result in your death, then that disease is incurable.

This seems obvious since, if the disease were curable, then you wouldn’t be expected to die from it.

But, what does it mean to be “incurable”? As a first pass, let’s say that for a disease to be incurable means that it cannot be corrected, remedied, or reversed.

An incurable disease might still be “treated” in some broad sense. For instance, an Alzheimer’s sufferer might receive pharmaceuticals that are intended to slow the progression of the disease or to minimize or eliminate behavioral problems that are byproducts of the Alzheimer’s. But, the Alzheimer’s “treatments” that are available are not expected or advertised to correct, remedy, or reverse the dementia.

Broad Vs. Narrow Definitions

Perhaps the best way to think about the idea of a “terminal illness” is to think of it as having a broad (or “loose”) sense and a narrow (or “strict”) sense.

Let me put it like this. On the broad usage, a terminal illness is one that negatively affects your lifespan. Additionally, since it is incurable (see above), you will still suffer from the disease when you die. Whether or not you actually die from Alzheimer’s or merely with Alzheimer’s is another matter. (For more on that question, see the companion article “How Does a Person Actually Die From Alzheimer’s Dementia?”)

This broad use of the term is common in everyday speech, where people often speak loosely. For example, when a person is angry, he or she might say, “I could just kill someone!” But there is usually no cause to believe that an bona fide murder is about to take place. The phraseology simply means that the speaker is really put out. Or, less violently – and perhaps more on-point – we might say that we’re suffering from the “stomach flu,” when we have some gastrointestinal distress. In fact, the word “flu” is short for influenza, which is a respiratory virus. But the fact that this designation is not strictly accurate is beside the point. The utterance means that the speaker has major stomach problems, and the hearers all get the point.

So, in the broad and loose sense, yeah, Alzheimer’s seems pretty terminal. There’s no cure. And you’re going to die with it. If you get it, it’s really bad. This is probably the point of the utterance in everyday speech. And the point is understandable.

But there is also a technical definition. If you have a long-term care insurance policy – or a life-insurance policy with a long-term care rider – you’re going to want to at least familiarize yourself with this definition as well.

On the narrow definition, a “terminal illness” is one that you are expected within a specified – and highly compressed – time period. Usually, we’re talking about death within twelve months of fewer. Certainly, no longer than twenty-four months.

Thus, on the narrow definition, we have to be a bit more careful with the way that we wield the word “terminal.” Think about a person who has just been diagnosed with mild-cognitive impairment (MCI) or with early-stage Alzheimer’s. In many cases, the prognosis may be relatively good (or at least, not horrendously poor) for several more years. A person in beginning stages may have a decade or more to live.

We can see that if a “terminal illness” is one for which death is expected within 1-2 years; but a newly diagnosed Alzheimer’s patient has (let’s assume) five to fifteen years to live; then it follows straightforwardly that such a condition would not count as terminal in the strict sense.

I hasten to remind readers, though, that Alzheimer’s is a degenerative or progressive condition. Whereas it may be true that “Alzheimer’s” (period) is not a terminal illness, we might say that late-stage Alzheimer’s arguably is.

This is because, in its advanced stages, the sufferer may very well be facing the prospect of dying within one to two years.

So, what is the verdict?

I’ll summarize it this way. Alzheimer’s – without qualification – is “terminal” in a broad or loose sense, but perhaps not in a technical sense. But, late-stage Alzheimer’s is likely terminal in both a broad sense and in the narrow (or strict) sense.

A Philosophical Footnote

Necessary Vs. Sufficient Conditions

To be more thorough about things, we should probably make a distinction between a necessary and a sufficient condition. You didn’t think you were going to have a philosophy lesson today, did you?

A necessary condition for something is a condition that has to be there for that something to exist. Consider the so-called “fire triangle.” If you have a fire, then you have oxygen present. Oxygen has to be present for you to have a fire. So, oxygen is necessary for a fire.

Similarly, being incurable seems like it’s a necessary condition for a disease to be terminal. Pneumonia isn’t, per se, incurable. Even though a lot of people die from pneumonia, having pneumonia isn’t a death sentence –all things being equal. I had pneumonia when I was twelve years old. I survived. Even my dad had pneumonia when he was 83 and in a nursing home with Alzheimer’s. He survived.

At the same time, being incurable isn’t – by itself – a reason to think that a disease is terminal. If incurability by itself were enough to classify a disease as terminal, then we would say that incurability was a sufficient condition for a disease being terminal.

Consider fires, again. Even though oxygen is necessary for fire, it isn’t sufficient. You don’t automatically get a fire whenever and wherever there is oxygen. You need some other stuff (like a fuel supply and a spark). On the other hand, think of cooking eggs. You can fry, poach, or scramble eggs. Any of these methods is sufficient to “cook” eggs. If you have fried eggs, then you have cooked eggs. You don’t need to do anything else other than fry an egg to get it cooked.

Herpes simplex viruses aren’t curable. According to the received medical opinions, if you contract herpes, you’ll have herpes for the rest of your life. It can be controlled, but it cannot be corrected, remedied, or reversed in any straightforward way. But, herpes isn’t “terminal.”

This shows that even though it is necessary, incurability isn’t sufficient for a disease to be terminal. Incurability is to terminal illness as oxygen is to fires.

For Related Information, see:

How Does a Person Actually Die From Alzheimer’s Dementia?

Disclaimer

I have repeatedly noted on this website, and I will say again, that I am not a doctor. I cannot give medical advice. The information in the post, and on ALZHEIMERSPROOF.com, is simply a collection of what I have come to believe — through personal experience and research. Although I present the information in good faith, I do not warrant that it is true.

How Does a Person Actually Die From Alzheimer’s Dementia?

According to several sources, Alzheimer’s ranks in the top ten (non-homicidal) causes of death, nationwide. The Centers for Disease Control and Prevention states that it’s number six,[1] behind heart disease (1), cancer (2), accidents (3), chronic respiratory diseases (4), and strokes (5). But, with these other conditions, the cause of death seems fairly intuitive – the heart stops (heart disease), a person cannot breathe correctly (lung disease), etc. What kills you when you have Alzheimer’s? There are basically three sets of possibilities.

When an Alzheimer’s-afflicted person passes away, most of the time, he or she dies from various conditions – such as blood clots, pneumonia, sepsis, etc. – that arise as complications to the Alzheimer’s. However, it is possible for a person to die from Alzheimer’s more directly, as when a person’s brain no longer supports crucial abilities like breathing air or swallowing food. Still others die from things like cancer, heart disease, or kidney problems that they happen to also have, but which have no express relationship to their dementia.

Alzheimer’s Disease is similar in some respects to (the received view on) Human Immunodeficiency Virus (HIV). When it comes to HIV, a person dies from “opportunistic infections,” after the HIV progresses into full-blown Acquired Immune Deficiency Syndrome (AIDS). A person with compromised immunity has, by definition, a severed diminished capacity for fighting off diseases and infections.

Similarly, many people won’t die from “Alzheimer’s” per se, but from the sorts of secondary conditions previously mentioned.

What Is Alzheimer’s?

This is not the place for an extended discussion of Alzheimer’s Disease. There are numerous resources online where interested readers can find this sort of information. (For ALZHEIMERSPROOF’s overview of the relevant condition, see HERE.)

However, it does seem appropriate to give a brief description. After all, Alzheimer’s (along with other forms of dementia) is a progressive condition. This mean, of course, that a patient gets worse over time.

The basic thing that happens to an Alzheimer’s-affected person is that his or her brain develops various “plaques” and “tangles.” These are proteins that have gone haywire and that negatively impact the brain’s ability to interface with the nervous system and the rest of the body.

Initially, the disease causes confusion along with emotional and personality changes. The memory deteriorates, and people lose high-level faculties such as reasoning and speech. Eventually, persons with dementia may “forget how,” or otherwise lose their abilities to, perform basic, life-sustaining functions. As the disease advances, sufferers begin to lose even low-level faculties, such as the ability to blink, to walk and, later, to register emotion, to swallow food and water, or even to breathe, cough, or sneeze.

Without these essential capabilities, Alzheimer’s sufferers are unable to clear debris, food, mucus, and so on from their airways. Ultimately, vital life functions simply slow down, then cease, due to decreased brain activity.

From onset to death, Alzheimer’s may last anywhere from four to fifteen years. From my research, common estimates range from six to eight years. But these are just rough figures. Every family’s experience is unique.

3 Stages of Alzheimer’s Disease Progression

  1. Early Stage – Characterized by a Person Having Subtle Behavioral Changes and Difficulty Recalling Newly Learning Information.
  2. Middle Stage – The Sufferer Displays More Pronounced Emotional Changes, Stemming From Increased Confusion and Disorientation, as Well as Decreased Language, Locomotive, and Memory Faculties.
  3. Late Stage – The Patient Loses All (or Almost All) Abilities to Move and Express Themselves. Ultimately, the Alzheimer’s-Affected Individual Is Unable to Perform Even Automatic Processes Like Breathing, Swallowing Food and Water, etc.

Is Alzheimer’s a ‘Terminal Illness’?

This question has a fair amount of subtlety. I have treated it at greater length HERE. But, suffice it to say that there are broad and narrow conceptions for what a “terminal illness” is.

On the broad conception, a terminal illness is merely one that reduces your life expectancy and that you will you will have at the time of your death. Alzheimer’s surely fits this general description.

On the narrow definition, a terminal illness is one that you are expected to die from very soon – maybe within twelve or twenty-four months. A person recently diagnosed with mild-cognitive impairment or early-stage Alzheimer’s may have eight to ten years to live. So, on this narrow definition, “Alzheimer’s” – by itself – may not be a terminal illness. However, we could say that late-stage Alzheimer’s could plausibly be construed as a terminal illness. Because, by the time a person enters Alzheimer’s advanced, end, or late stage, it may well be that their life expectancy has been reduced to one or two years.

For a more in-depth discussion of this issue, click HERE.

What Are Some Complications?

At some point, virtually all Alzheimer’s patients will have problems eating. They may stop eating entirely. This straightforwardly leads to malnutrition, weakness, weight loss, and starvation.

As mentioned, above, many Alzheimer’s-afflicted individuals lose the ability to walk. This general immobility leaves the person variously bedridden or wheelchair bound. Normal-functioning people may be at greater risk for health problems when they lead a sedentary lifestyle. But to be more or less completely stationary is much worse. Being motionless in this way can lead to bed sores (which, untreated, can get infected) and blot clots (which can be very serious, especially if they travel to the heart, lungs, etc.).

In advanced stages, the brain degenerates to the point where it is unable to properly regulate the body.[2] This irregularity can precipitate all sorts of problems, including weakened immunity.

“Aspiration” occurs when a person accidentally inhales bits of food or drops of water. These then end up in the lungs. Without the ability to expel these foreign materials by coughing or sneezing, the individual is at great risk for infections and pneumonia.

Moreover, immune-compromised persons are more susceptible to infections and can develop serious conditions like sepsis.

What Goes on, Medically?

Medically, what goes on depends on which of the three possibilities obtains.

Suppose that the Alzheimer’s patient passes from a secondary condition. Then the medical cause of death will depend on the particulars of that condition. So, suppose that an immobile Alzheimer’s patient develops a blood clot in his or her calf. Doctors will try to treat the clot by using blood thinners. But, if the clot breaks loose a person can die any or three ways. Firstly, the clot could block an artery. This may happen any number of places, but it is most dangerous around the lungs. Called a “pulmonary embolism,” a blood clot near the lungs can cut off oxygen to the body and brain. Secondly, the clot could cause the person to go into cardiac arrest. If the clot passages into the heart, the heart’s pumping may become erratic and fatal arrhythmias may develop. Thirdly, the clot could go towards the brain, block an artery there, and cause a fatal stroke.

If a person develops pneumonia, then the main risk is that of infection. Pneumonia is characterized by a person’s having “fluid-filled” sacs in the lungs. In the first place, the fluid impedes the lung’s ability to pass oxygen into the blood stream. But the fluid is also a breeding ground for bacteria. This bacteria can make its way into the blood, travel around to other organs, and cause a massive, whole-body infection that a person is unlikely to recover from.

Suppose, instead, that the individual dies from an unrelated condition. Of course, most people suffering from Alzheimer’s Disease are aged. In virtue of this fact alone, a person who has Alzheimer’s might also have other heath problems, such as cancers of various kinds, heart disease, kidney disease, and so on. If an Alzheimer’s-afflicted person dies from one of these unrelated conditions, then their cause of death will be identical to the cause in a non-Alzheimer’s-affected person who died of the same condition. To put it differently, if a person dies from something like a heart attack, then the fact that a person also has Alzheimer’s has no medical effect on the cause of death in that case.[3]

Finally, suppose that a person expires in late stage, when they lose abilities like breathing or swallowing food and water. In this, final set of cases, the lost abilities (e.g., swallowing water) virtually ensure that the person’s body systems will being to “shut down.” Without proper hydration, kidney failure will ensue. Without proper oxygenation, the body and brain tissue will die.

None of these descriptions paint a happy picture, I realize. My sympathies are with you and your family. The best that I can say is that I can appreciate what you’re going through, since my family went through something of the same thing.

What Was My Experience With My Dad?

As I have shared in other places (see HERE), my dad, Jim, had Alzheimer’s for about ten years. In retrospect, his doctors led us to believe that he had been suffering through early stages of the disease before it was recognized for what it was. During that period of uncertainty, I attributed his attitude and behavioral changes to his becoming crotchety and temperamental.

But, most relevantly, he was diagnosed with arterial blockages and colon cancer. We nursed him through a triple bypass operation and a colectomy. I say that to mention this: For his age, my dad was otherwise physically healthy when his Alzheimer’s was finally diagnosed.

When he underwent heart surgery, he was literally at death’s door, and he could have expired at any moment. But having had the two surgical interventions, he lived through a full progression of the various stages of his dementia.

We noticed (of course) the locomotive and speech degeneration that is typical of Alzheimer’s. Indeed, there were several episodes when he developed blood clots, pneumonia, and urinary-tract infections. He contracted a severe respiratory virus at least once and had a gastro-intestinal bug on another occasion. Any of these events could have resulted in his death. And Jim came close to dying during a few of them.

But, he didn’t.

He held on. He came back.

He went into hospice care at least five times. And four times recovered enough to go off hospice.[4]

By the end, Jim was unable to move at all. He just lay on his back, staring off into space with increasingly cold and distant eyes.

Whereas I (and my mom and sister) had expected him to die from some complication, in the end, he seemed to die from the effects of the brain deterioration.

He was unable to swallow – either food or water. And he struggled to breathe. Jim would take a couple of breaths and then he would give a low-volume gasp – almost like a person taking a deep breath. And then he wouldn’t make any sound for a few seconds before another raspy breath would escape and the process would repeat.

He lasted in this state for about ten days.

I remember sitting at his bedside, expecting period of silence to be “it.” He persisted.

I recall asking a hospice nurse how long a person could go without food or water. She stated that everyone was different. She had seen some people hang on for a day or so. Another might take a week. According to her, one person had gone nearly a month.

This was exasperating news.

We felt that he might be “waiting” for something. We told him it was all right go. We arranged for various rituals to be performed, according to his religious tradition. But still his condition remained more or less unchanged.

Though, Jim’s toes began to turn blue.

Finally, my sister and her family were able to make arrangements and began to make their way by car. I didn’t really think they would come in time. My mom and I took turns rubbing my dad’s feet to help them return to a healthier color.

It took my sister and her family around fifteen hours to arrive. When she came into the room, she walked around his bed to position herself in front of him. Remarkably, he turned a bit and his mouth moved as if he had something to say. No sound came out. But he had been entirely motionless until then.

Nothing happened immediately. We all sat with him for several hours, discussing what to do.

I ended up staying with him that night. My mom and sister came to relieve me in the morning. I went home to spend time with my two sons and to rest, expecting to have to spend another night with my dad.

But it was not to be.

My sister called me at 1:15 pm to let me know that my dad had died. I remember groaning, “Oh, no.” My first thought was that I had been glued to my dad for the past week because I wanted to be there when it happened.

My reassured me by saying, “No; that is a good thing.” And I realized that my desire to be there was self-centered. If I had been a comfort to my dad, then that is what really mattered.

My sister related that she and my mom had not been in the room when it occurred. Everyone had stepped out to allow a cleaning person to tidy up. Some observers have commented that Jim passed while he had a moment of privacy.

For more on Jim’s story, read my account, HERE.

3 Ways to Die – Summarized

  1. Alzheimer’s Causes a Fatal Secondary Condition (E.g., a blood clot or pneumonia, etc.)
  2. The Alzheimer’s Patient Also Has Some Other, Unrelated Condition (E.g., cancer or heart disease, etc.) and He or She Dies From That
  3. Alzheimer’s Disease Runs to Its Advanced Stage Where a Person Loses Life-Sustaining Functions (E.g., breathing and swallowing food) and the Person Basically Suffocates or Starves

Notes:

[1] There are some subtleties, here. A number of writers worry that the number of Alzheimer’s-related deaths are underreported, due perhaps to the fact that an Alzheimer’s sufferer often develops complications. So, if a person with Alzheimer’s contracts and dies from pneumonia (for more on which, see further along in the main text), the medical examiner may report the death as a due to pneumonia, rather than to Alzheimer’s. On the other side of things, it may be that the number of Alzheimer’s deaths is overreported. Some authorities maintain that the only sure-fire way to verify that a person’s condition is actually Alzheimer’s – as opposed to some other sort of dementia or condition – is to perform an autopsy. However, it may be that may people whose death certificates read “Alzheimer’s” have only had a physician’s diagnosis of the condition and never underwent a postmortem examination.

[2] It fails to maintain “homeostasis.”

[3] True, there might be other, non-medical factors. For example, if a person with Alzheimer’s begins having chest pains, he or she may not have the presence of mind or the ability to report this. These inabilities might raise the probability that an Alzheimer’s sufferer will die from the heart attack – whereas a non-Alzheimer’s sufferer might survive, if he or she can call for help, pop an aspirin, etc.

[4] When a person goes into a nursing home, their vital statistics (like height, weight, food intakes, etc.) are recorded. Our experience with hospice was that when my dad fell below – by some degree or other – his “baseline” statistics, he would qualify to go on hospice care. But whenever he regained his weight and appetite, he would be reentered into the general population.

Disclaimer

I have repeatedly noted on this website, and I will say again, that I am not a doctor. I cannot give medical advice. The information in the post, and on ALZHEIMERSPROOF.com, is simply a collection of what I have come to believe — through personal experience and research. Although I present the information in good faith, I do not warrant that it is true.

Can Contaminated/Dirty Tap Water Cause Alzheimer’s Disease?

Current research suggests that Alzheimer’s-Disease susceptibility roughly corresponds to a 70-30 formula. To be specific, around 70% of your risk will be inherited risk. This is the risk that’s built into your family health history, and it may be measurable with a genetic test. (For more on such a genetic test, see HERE.) That leaves 30% of your risk to fall on non-genetic factors. This is the portion of your risk that comes from your behaviors, your environment, and so on.

Although it has not been definitively established by scientists, it is reasonable to think that exposure to contaminated drinking water can constitute a significant risk to our health. Even in first-world countries, water contamination is a serious problem. From naturally occurring compounds like bacteria and heavy metals to industrial waste products like pesticides and pharmaceuticals, the junk in our drinking water could be – at least partly – responsible for the brain inflammation and toxicity that is characteristic of Alzheimer’s.

Background

As General Jack Ripper (played by Sterling Hayden) put it in Stanley Kubrick’s 1964 film, Dr. Strangelove: “Water. That’s what I’m getting at: water. …Why, do you realize that 70 percent of you is water?” That may be overstating things a bit. Figures vary. But, indeed, human beings are arguably upwards of 50% water.

To put it another way, our bodies are literally saturated with water, and we require clean, fresh water to live. General Ripper, as kooky as he may have been, got that bit right. Even a broken clock is correct twice a day!

The sad – and somewhat shocking – fact is, however, that our drinking water isn’t as clean as we might hope. And it’s a lot, well… dirtier than many people are aware.

According to one article, in the U.S. alone, “…29 million people [are] drinking water that missed the mark on either health or reporting standards.”[1] And that just means that their drinking water isn’t as clean as the bare minimum required by governing regulations.

But, regulations sometimes allow quite a bit to get through.[2] And, in other cases, polluting materials can work their way into the water between the processing facility and your drinking glass.

The contaminants found in drinking water could lead to cell and tissue damage in almost any part of our body. But perhaps the scariest thing to consider – and our present focus – is the potential for damage to our brains and nervous systems.

The brain is somewhat insulated from run-of-the-mill contaminants by something called the “blood-brain barrier.” Without getting into the physiological details, this barrier is a byproduct of the function of brain and spinal blood vessels. It effectively blocks many, but not all, harmful substances from getting to our master control center.

There is little question but that we are daily exposed to environmental toxins. To get a fix on the scope of the problem, look at a list of some of the things that might show up in drinking water. Bear in mind that not every area will be equally polluted. Not all these chemicals (or other compounds) are found in every water sample. But this list – although it is not exhaustive – can give you an idea of why this may very well be a problem.

List of Some Contaminants Possibly Found in Municipal Water

Inorganic Materials

To flash back to high school chemistry, I note that “inorganic” matter is that which does not contain carbon. That clears it right up, doesn’t it? Take heart, the actual chemical properties are of secondary importance in the present context. The basic point that I am making is that there is a lot of crud in our water supply.

Contaminants include the following.

Heavy Metals

Heavy metals run the gamut in terms both of effects on health as well as of source. Take aluminum, for instance. In 1989, the vaunted Chicago Tribune reported: “Fact No. 1: High levels of aluminum have been found in the brains of victims of Alzheimer’s disease… Fact No. 2: An aluminum compound is commonly used to purify public drinking water supplies. Fact No. 3: Neither the federal nor the state government has set standards for the amount of aluminum that is allowed in drinking water.”[3]

Even if the water coming into your home is clean – and, chance are, it isn’t – the fact is that it can become contaminated by your own pipes. “…Low levels of lead exposure are linked to damage to a child’s blood cells and nervous system, as well as learning disabilities, poor hearing, impaired growth and more. …Lead ‘bio-accumulates’ in the body, which means it stays and builds up over time, so ongoing exposure, even at extremely low levels, can become toxic. …[L]ead can enter your home when lead plumbing materials, which can include faucets, pipes, fittings and the solder that holds them all together, become corroded and begin to release lead into the water.”[4]

Well water is by no means perfect, either. Another example? Iron, which is mostly found at low levels, can harbor bacteria (on which, see more, below). “…[I]ron sediments may contain trace impurities or harbor bacteria that can be harmful. Iron bacteria are naturally occurring organisms that can dissolve iron and some other minerals. These bacteria also form a brown slime that can build up in water pipes. Iron bacteria are most commonly problematic in wells, where water has not been chlorinated.”[5] (But on the health risks of chlorination, see further down.)

Or, again, according to the United States Environment Protection Agency (EPA), inorganic mercury usually comes from “erosion of natural deposits; discharge from refineries and factories; runoff from landfills; and runoff from croplands.”[6] “High exposure to inorganic mercury may result in damage to …the nervous system… Symptoms of high exposures to inorganic mercury include: …memory loss …[and] mental disturbances…”.[7]

Heavy Metals at a Glance:

  • Aluminum
  • Antimony
  • Barium
  • Beryllium
  • Bismuth
  • Cadmium
  • Cobalt
  • Chromium
  • Copper
  • Iron
  • Lead
  • Mercury
  • Molybdenum
  • Nickel
  • Silver[8]
  • Vanadium
  • Zinc

Medical Compounds

“A vast array of pharmaceuticals including antibiotics, anti-convulsants, mood stabilizers and sex hormones have been found in the drinking water supplies of at least 41 million Americans… [T]he concentrations of these pharmaceuticals are tiny, …[b]ut the presence of so many prescription drugs and over-the-counter medicines like acetaminophen and ibuprofen in so much of our drinking water is heightening worries among scientists of long-term consequences to human health.”[9]

One upsetting aspect of this is the fact that the Environmental Protection Agency does not officially track the presence of pharmaceuticals in drinking water. Peruse the list of 90 or so chemicals that it does monitor, and you won’t find any mention of either prescription or over-the-counter medications.[10]

 

Pharmaceuticals at a Glance:

  • Analgesics or NSAIDs (Acetaminophen, Aspirin, Carbamazepine, Diclofenac, Fentanyl, Hydrocodone, Ibuprofen, Naproxen, Oxycodone, etc.)
  • Antibiotics (Ciprofloxacin, Erythromycin, Penicillin, Sulfamethoxazole, Trimethoprim), Barbiturates (Clonazepam, Phenobarbital, Primidone, etc.)
  • Disinfectants (Chloramine, Formaldehyde, Triclosan, etc.)
  • Hormones (Estrogen, Progesterone/Progestin, Testosterone, etc.)
  • Simulants (Amphetamine [Adderall], Caffeine, methylphenidate [Ritalin], etc.)

Metalloids

In 2013, the New York Times, America’s “newspaper of record,” reported on a “a toxic element common in drinking water.”[11] The element in question? The well-known slow-acting poison arsenic!

“It seeps into groundwater[.] …[F]or many years its presence was mostly noted and dismissed by public health researchers. They’ve changed their minds. Long famed for its homicidal toxicity at high doses, a number of studies suggest that arsenic is …able to do damage even at low doses.”

Metalloids at a Glance:

  • Arsenic
  • Selenium

Potentially Harmful Gases

An article in Scientific American reported on the fact that “[a]lthough chlorine is widely used as an effective way to disinfect drinking water, researchers are concerned that it can lead to bladder, rectal and breast cancers.”[12]

Gases at a Glance:

  • Ammonia
  • Chlorine

Miscellaneous Chemicals

This category could be wide-ranging. But I will simply note that a few chemicals – like haloacetic acids and trihalomethanes – are formed as by-products of the chlorination process. Basically, hazardous chemicals can be formed in attempts to disinfect the water supply.

“[C]hlorine [see above] …interacts with organic compounds to create trihalomethanes (THMs)—which when ingested encourage the growth of free radicals that can destroy or damage vital cells in the body.”[13] “The trihalomethanes and haloacetic acids have demonstrated carcinogenic activity in laboratory animals.”[14]

Miscellaneous Chemicals at a Glance:

  • Haloacetic Acids
  • Octylphenols
  • Nonylphenols
  • Trihalomethanes

Radioactive Compounds

“Does your tap water contain the radioactive element radium? You might be surprised to hear that tap water for more than 170 million Americans contains the compound…”.[15] “Radium in water may pose a hazard to human health when the water is used for drinking or cooking. …Absorbed radium …is deposited in the tissues of the body, especially bone …[,] emits alpha particles[,] …[and] may …damage surrounding tissue.”[16]

Although not as widespread of a risk, uranium is also found in some U.S. drinking-water samples. One recent headline declared: “6 million U.S. residents are drinking uranium-contaminated water…”.[17]

Radioactive Compounds at a Glance:

  • Radium (Ra-226, Ra-228)[18]
  • Uranium[19]

Organic Materials

“Organic” materials are those that do contain carbon. Usually, these are the things that are “associated” with living matter. But, again, even if my taxonomies are a bit off, the underlying purpose of this list is simply to help readers get a handle on the scope of the possible contamination.

Potentially Harmful Salts

“[N]itrate …[is] a common groundwater contaminant …that stems from chemical and animal waste fertilizers. …Nitrate has …adverse health effects on humans…”.[20]

Salts at a Glance:

  • Chloride
  • Fluoride
  • Nitrate
  • Nitrite
  • Perchlorate

Viruses & Bacteria

Let’s start off with an example that really shocked me when I found out about it. Ever heard of Salmonella? That’s exclusive to raw eggs, right? Anyway, that’s what I thought; but, no!

In 2008, residents of one Colorado town were sickened by Salmonella – in their tap water. “State health officials warned residents of a southern Colorado town Wednesday to stop drinking and cooking with tap water because they said it might be linked to a salmonella outbreak.”[21]

The presence in drinking water – and even municipal tap water – of various viruses and bacteria has been documented in several peer-reviewed scientific journals.[22] Most of these critters have scary names, like Legionella pneumophila.[23]

Bacteria & Viruses at a Glance:

  • Adenovirus
  • Anabaena circinalis
  • Astrovirus
  • Bacillus atrophaues
  • Bacteriophage MS2
  • Calicivirus (Norwalk)
  • Coliform bacteria (e.g., e. Coli)
  • Cytomegalovirus[24]
  • Enterovirus (e.g., Coxsackie A & B, ECHO, Poliovirus)
  • Giardia lamblia (“Beaver Fever”)
  • Hepatitis A and E
  • Legionella pneumophila (“Legionnaires’ Disease”)
  • Norovirus, Polyomavirus[25]
  • Raoultella terrigena
  • Rotavirus
  • Salmonella Enterica.

Fungi

“Tap water is a potential site of pathogenic fungal contamination and may be a particular concern even in urban areas of developing nations. …In the United States, …drinking water is considered ‘among the safest in the world’… . Nevertheless, pathogenic fungi can still enter drinking water in developed nations, including all types of treated tap and bottled water.”

Fungi at a Glance:

  • Acremonium
  • Aspergillus
  • Candida (albicans, parapsilosis)
  • Chaetomium
  • Cladosporium
  • Exophiala dermatitidis
  • Fusarium
  • Microsporidia
  • Mycelia
  • Paecilomyces
  • Penicillium
  • Trichoderma

Parasites

Parasites are some of the creepiest things on my list. They may or may not be the most damaging among the other tap-water difficulties that we’ve surveyed. But they certainly have a high “ick factor.”

Could it be a problem? The Minnesota Department of Health once reported: “In April 1993, an intestinal parasite called Cryptosporidium was responsible for a major outbreak of illness in the city of Milwaukee, Wisconsin. More than 400,000 people became ill after drinking contaminated water from the city water supply system.”[26]

Parasites at a Glance:

  • Cryptosporidium parvum
  • Rotifera

Pesticides

Is this really a concern? Here’s what the Washington Post revealed under the title ““First Evidence Found of Popular Farm Pesticides in Drinking Water”: “…[S]cientists studying the country’s waterways [have] started to detect neonicotinoid pollutants. In 2015, the U.S. Geological Survey collected water samples from streams throughout the United States and discovered neonicotinoids in more than half of the samples. …[More recently,] …chemists and engineers at the USGS and University of Iowa reported that they found neonicotinoids in treated drinking water.”[27]

There are a million pesticides and other volatile compounds. Virtually all of them have ponderous chemical names. I will not try to make an exhaustive list but will satisfy myself with hitting a few of the highlights.

Pesticides at a Glance:

  • Acenaphthylenes
  • Bromofluorobenzenes
  • Bromomethanes
  • Chlorobenzenes
  • Chloroethanes
  • Chlorotoluenes
  • Dichloroethanes
  • Dichloroethylenes
  • Dichloropropanes
  • Ethylbenzenes
  • Glyphosates
  • Hexachlorobenzenes
  • Hexachlorobutadiene
  • Isopropylbenzenes
  • Isopropyltoluenes
  • Monochlorobenzenes
  • Pentachlorophenols
  • Naphthalenes
  • Tetrachloroethanes
  • Trichlorobenzenes
  • Trichloroethanes
  • Trichlorofluoromethanes
  • Trichlorotrifluoroethanes

Is Bottled Water a Viable Alternative?

Possibly. It may be much better than certain municipal water supplies. But consider a couple of things.

First, various water-bottling facilities get their source water from municipal water. Thus, in cases like this, unless there is considerable secondary purification at the bottling facility, it is likely that your bottled water is only as good as the run-of-the-mill tap water.

This might be why one journalist disclosed that she was told by an EPA employee: “with bottled water ‘it’s a crapshoot what you’re getting.’”[28]

Another writer stated flat-out: “don’t think that buying bottled water is any solution.”[29]

Sometimes bottled water can introduce new hazards. For example, “…bottled water is tested at the plant, not after it’s been sitting in plastic for up to two years. Chemicals from bottles have been shown to leach into water over time.”[30]

So, second, chemicals like Bisphenol A (also called BPA) – which may not be in tap water – can get into your bottled water. According to an article on the website of the prestigious Mayo Clinic: “BPA is an industrial chemical that has been used to make …polycarbonate plastics… . Polycarbonate plastics are often used in …water bottles.”[31]

One recent “study show[ed] that BPA is a ubiquitous contaminant in surface, tap and bottled mineral water.”[32]

True, it is usually present in “[l]ow levels.”[33] But, according to some sources, “BPA is a micropollutant, a type of everyday chemical that can affect people even in low doses. Most of our exposure comes from canned food and plastic food and drink containers. Studies have also shown that the chemical is found in …drinking water.”[34]

“…BPA [is] detect[able] in most …drinking water samples. BPA in tap water …[is worst] in samples collected from taps connected to PVC pipes and water filter devices. Bottled mineral water had lower levels of BPA …[,] although samples stored in poor storage condition had significantly higher levels… .”[35]

How Can You Protect Yourself From Contaminated Water?

The really disturbing part is that our water-treatment facilities seem to be inadequate in many ways.

For example, some contaminants are allegedly traceable “to the water treatment process” itself.[36] We’ve already seen (above) that the primary means of disinfection – water chlorination – can actually precipitate chemicals (like trihalomethanes) that are (probably) carcinogenic. Even some carbon-element filters can harbor bacteria. This is why, once upon a time, water-filter elements were impregnated with silver. (For more on silver – including its alleged antibiotic properties – and how it can possibly make sense to include it in your diet, see HERE.)

And if, as we just mentioned in the previous section, bottled water leaves something to be desired. What is there left to do?

It turns out that, even if you have access to it, the “raw” water right out of a stream may not be the best choice either. It can be teeming with all sorts of environmental toxins, parasites, and pollutants.[37] Is there anything that we can safely drink?

Hope is not lost. But it may be wise to implement a multi-layered strategy. For instance, you’ll definitely want to employ some sort of water filter in your home.

Purification Methods

“[A] variety of methods may be used to remove potentially harmful microorganisms from the water supply. …[T]he most common methods to treat community water supplies (particularly when the source is surface water, which is generally more prone to significant contamination then groundwater) include coagulation and flocculation (positively charged chemicals are added to bind with negatively charged dirt and other particulate matter), sedimentation of these now larger particles, filtration using natural and artificial filters, and disinfection with chemicals such as chlorine or chloramine (often done as the final step in water purification).”[38]

Boiling

Boiling is a highly effective way to kill pathogenic (and other) microorganisms. Most microorganisms are unable to survive in water temperatures between 160° and 185° Fahrenheit (70°-85° Celsius). Therefore, bringing a water sample to a full boil – usually, at 212° F (100° C) – will more or less completely eradicate pathogens. Boiling for a few minutes virtually ensures that the sample will be clean.[39]

However, boiling will not remove (all) chemical pollutants. (Although, possibly, some may evaporate.) Other processes are required for total water purification.

Coagulation

The process of water coagulation involves the introduction of a chemical (e.g., alum) that causes microscopic contaminants to “clump,” allowing them to be more easily filtered out of the water.

BPA removal:

A sort of coagulation process is used in the removal of Bisphenol A, or “BPA.” “Terrence Collins at Carnegie Mellon University in Pennsylvania and his colleagues set out to find a cheap way to remove BPA from water. After 15 years of work, the team came up with a solution: first, they add a group of catalysts called TAML activators to contaminated water, next they add hydrogen peroxide.

“The TAML activators work much like the enzymes in our bodies do, speeding up chemical reactions. In combination with the hydrogen peroxide, the TAML activators cause the BPA in pH-neutral water – the typical pH of wastewater – to assemble into larger clumps called oligomers within 30 minutes. These clumps aren’t harmful, and can be easily filtered out of the water.”[40] (On filtration, see below.)

Disinfection

“Disinfection” has several, possible meanings. Most generally, it simply refers to the counteraction of an “infection” – which, in this case, basically amount to the presence of some kind of microorganism (perhaps pathogenic) in the water supply. Now the “infection” of a water sample could be countered by removing the relevant microorganism. In this sense, purification methods such as filtration could be considered “disinfection” methods.

Chlorine

However, on most common usage of the word, what is in view is the deactivation or killing of a pathogen by chemical means. Under this definition, the primary method of disinfection at the municipal level is chlorination.

“Chlorination is the process of adding chlorine to drinking water to disinfect it and kill germs. Different processes can be used to achieve safe levels of chlorine in drinking water. Chlorine is available as compressed elemental gas, sodium hypochlorite solution (NaOCl) or solid calcium hypochlorite (Ca(OCl)2. While the chemicals could be harmful in high doses, when they are added to water, they all mix in and spread out, resulting in low levels that kill germs but are still safe to drink.”[41]

Iodine

“Iodine has been shown to be more effect than chlorine-based treatments in inactivating Giardia cysts. Be aware that some people are allergic to iodine and cannot use it as a form of water purification. Persons with thyroid problems or on lithium, women over fifty, and pregnant women should consult their physician prior to using iodine for purification. Also, some people who are allergic to shellfish are also allergic to iodine. If someone cannot use iodine, use either a chlorine-based product or a non-iodine-based filter… Iodine is light sensitive and must always be stored in a dark bottle.”[42]

Flocculation

Coagulation is employed in conjunction with a process known as “flocculation.” In this process, the water is stirred in such a way as to prompt the smaller clumps to group together.

Sedimentation

In the sedimentation process, suspended particles basically “fall” in the water and come to rest at the bottom of the containing vessel where, in principal, they can be readily removed.

Letting Your Water ‘Sit’

Some people will pour a glass or pitcher of water and then it sit. The idea is to allow chlorine to “vent” – or “off gas” – out of the water. Online, I have seen various time recommendations. But a few that recur involve letting the water sit overnight or for 24 hours.

Whether this method is effective or not is unclear. And, in any case, it will probably only remove gaseous chlorine. You will still need a method to address other chemicals and pathogens, if they are issues in your area.

Filtration

Oftentimes, water can be “filtered.” This means that the water is made to pass through a porous piece of material – called the filter or filter element. The idea is that the pores in the material are small enough that fine particles are unable to pass through and are thus removed from the water sample.

This is probably the most widespread and accessible method for home water purification. (For our specific product suggestions, see below.)

Conclusion

While there is certainly nothing like a scientific consensus that Alzheimer’s Disease or any other form of dementia is caused by dirty, contaminated, or otherwise polluted drinking water, there are genuine concerns. Chemical and pathogenic biological materials find their ways into the water supply – and, often, our drinking cups. Some of these contaminants are suspected of having negative effects upon the human nervous system and brain. Others are known to cause inflammation of body tissues, or even are thought to be contributing causes to various cancers.

Thus, I would put my tentative conclusion like this. From a theoretical perspective, I don’t know whether to worry about my tap water putting me at risk of Alzheimer’s. But, from a practical point of view, that is because I have gotten into the habit of purifying my water before I drink it. I suggest that you think about doing the same thing.

I See the Problem! What’s the Solution?

There are a number things that you can do, today, to improve the quality of your water. One thing that I recommend is obtaining a good quality filter system and water-disinfecting tablets (as backups).

For Alzheimer’sProof’s recommended water-purification products, see HERE.

Notes

[1] Elizabeth Royte, “Tap Water’s Dirty Little Secret,” Huffington Post, Sept. 18, 2008, updated May 25, 2011, <https://www.huffingtonpost.com/elizabeth-royte/tap-waters-dirty-little-s_b_119590.html>.

[2] According to (my reading of) a post on the Environmental Protection Agency’s (EPA’s) website, many unregulated chemicals include fuel additives, herbicides, and pesticides such as: “1,2-diphenylhydrazine; 2,4,6-trichlorophenol; 2,4-dichlorophenol; 2,4-dinitrophenol; 2,4-dinitrotoluene; 2,6-dinitrotoluene; 2-methyl-phenol; 4,4′-DDE; Acetochlor; Aeromonas; DCPA di-acid degradate; DCPA mono-acid degradate; Diazinon; Disulfoton; Diuron; EPTC; Fonofos; Linuron; MTBE; Molinate; Nitrobenzene; Nitrobenzene; Perchlorate; Prometon; Terbacil; and Terbufos. And these are just the ones that the EPA required water facilities to monitor.

[3] Stevenson Swanson, “Aluminum in Tap Water Worries Experts,” Chicago Tribune, Dec. 10, 1989, <https://www.chicagotribune.com/news/ct-xpm-1989-12-10-8903160868-story.html>.

[4] Sandee LaMotte, “How to Test for Lead in Your Home Water Supply,” CNN, Feb. 10, 2016, <https://www.cnn.com/2016/01/21/health/lead-testing-home-drinking-water/index.html>.

[5] Karen Garvin, “Health Effects of Iron in Drinking Water, LiveStrong, Oct. 3, 2017, <https://www.livestrong.com/article/158629-health-effects-of-sulfur-in-water/>.

[6] “How Does Mercury Get Into My Drinking Water?” Ground Water and Drinking Water Fact Sheets, EPA, <https://safewater.zendesk.com/hc/en-us/articles/212076067-5-How-does-mercury-get-into-my-drinking-water>.

[7] “Health Effects of Exposures to Mercury,” (EPA), Feb. 16, 2018, <https://www.epa.gov/mercury/health-effects-exposures-mercury>.

[8] Silver can have salubrious effects.

[9] Jeff Donn, Martha Mendoza, and Justin Pritchard, “Pharmawater I: Pharmaceuticals Found in Drinking Water, Affecting Wildlife and Maybe Humans,” Associated Press, <http://hosted.ap.org/specials/interactives/pharmawater_site/day1_01.html>.

[10] Things Tested for by the EPA include: Microorganisms [Cryptosporidium; Giardia lamblia; Heterotrophic plate count HPC]; Legionella [Legionnaire’s Disease]; Coliforms [including fecal coliform and E. Coli]; Turbidity; Viruses [enteric]), Disinfection Byproducts (Bromate; Chlorite; Haloacetic acids [HAA5]; Trihalomethanes), Disinfectants (Chloramines [as Cl2]; Chlorine [as Cl2]; Chlorine dioxide [as ClO2]), Inorganic Chemicals (Antimony; Arsenic; Asbestos; Barium; Beryllium; Cadmium; Chromium; Copper; Cyanide [free]; Fluoride; Lead; Mercury [inorganic]; Nitrate; Nitrite; Selenium; Thallium), Organic Chemicals (Acrylamide; Alachlor; Atrazine; Benzene; Benzo[a]pyrene [PAHs]; Carbofuran; Carbon tetrachloride; Chlordane; Chlorobenzene; 2,4-D; Dalapon; 1,2-Dibromo-3-chloropropane [DBCP]; o-Dichlorobenzene; p-Dichlorobenzene; 1,2-Dichloroethane; 1,1-Dichloroethylene; cis-1,2-Dichloroethylene; trans-1,2-Dichloroethylene; Dichloromethane; 1,2-Dichloropropane; Di[2-ethylhexyl] adipate; Di[2-ethylhexyl] phthalate; Dinoseb; Dioxin [2,3,7,8-TCDD]; Diquat; Endothall; Endrin; Epichlorohydrin; Ethylbenzene; Ethylene dibromide; Glyphosate; Heptachlor; Heptachlor epoxide; Hexachlorobenzene; Hexachlorocyclopentadiene; Lindane; Methoxychlor; Oxamyl [Vydate]; Polychlorinated biphenyls [PCBs]; Pentachlorophenol; Picloram; Simazine; Styrene; Tetrachloroethylene; Toluene; Toxaphene; 2,4,5-TP [Silvex]; 1,2,4-Trichlorobenzene; 1,1,1-Trichloroethane; 1,1,2-Trichloroethane   ; Trichloroethylene; Vinyl chloride; Xylenes), and Radionuclides (Alpha particles; Beta particles; photon emitters; Radium 226, Radium 228, Uranium). “National Primary Drinking Water Regulations,” Environmental Protection Agency (EPA), Mar. 22, 2018, <https://www.epa.gov/ground-water-and-drinking-water/national-primary-drinking-water-regulations>.

[11] Deborah Blum, “The Arsenic in Our Drinking Water,” New York Times, Sept. 20, 2013, <https://well.blogs.nytimes.com/2013/09/20/the-arsenic-in-our-drinking-water/>.

[12] “Tapped Out?: Are Chlorine’s Beneficial Effects in Drinking Water Offset by Its Links to Cancer?” n.d., <https://www.scientificamerican.com/article/earth-talks-tapped-out/>.

[13] “Tapped Out?: Are Chlorine’s Beneficial Effects in Drinking Water Offset by Its Links to Cancer?” n.d., <https://www.scientificamerican.com/article/earth-talks-tapped-out/>.

[14] Michael Hiscock and Michael Pereira “Health Risk of the Trihalomethanes Found in Drinking Water Carcinogenic Activity and Interactions,” Medical College of Ohio in conjunction with the U.S. Environmental Protection Agency, Jan. 8, 2000; updated online Nov. 29, 2018 <https://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.highlight/abstract/22>.

[15] Rachael Rettner, “Is There Radium in Your Tap Water? New Map Can Show You,” Live Science, Jan. 11, 2018, <https://www.livescience.com/61397-tap-water-radium.html>.

[16] “Radium in Drinking Water,” Illinois Department of Public Health, Jan. 2008, <http://www.idph.state.il.us/envhealth/factsheets/radium.htm>.

[17] Barbara Tasch, “6 Million U.S. Residents Are Drinking Uranium-Contaminated Water That Could Increase Risk of Liver Damage,” Business Insider, Aug. 18, 2015, <https://www.businessinsider.com/high-uranium-levels-of-drinking-water-in-the-central-us-2015-8>.

[18] To see a map of areas with tap water containing detectable levels of radium, click HERE.

[19] See a map, HERE.

[20] Barbara Tasch, “6 Million U.S. Residents Are Drinking Uranium-Contaminated Water That Could Increase Risk of Liver Damage,” Business Insider, Aug. 18, 2015, <https://www.businessinsider.com/high-uranium-levels-of-drinking-water-in-the-central-us-2015-8>. Nitrate also exacerbates the uranium problem (on which, see above), as it can render the compound water soluble. Ibid.

[21] “Salmonella Outbreak Linked to Tap Water: Illness Has Sickened Dozens in Colorado Town, Officials Say,” NBCNews.com, Mar. 20, 2008, <http://www.nbcnews.com/id/23726402/>.

[22] K. Botzenhart, “Viren im Trinkwasser” [“Viruses in Drinking Water”], Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz [“Federal Gazette for Health Research”], vol. 50, no. 3, Mar. 2007, pp. 296-301, German <https://link.springer.com/article/10.1007/s00103-007-0155-4>, English: <https://www.ncbi.nlm.nih.gov/pubmed/17334891>.; and Aimee Gall, Benito Mariñas, Yi Lu, and Joanna Shisler, “Waterborne Viruses: A Barrier to Safe Drinking Water,” Pathogens, Public Library of Science (PLoS), vol. 11, no. 6, Jun. 25, 2015, <https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004867>.

[23] See p. 33, <https://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1262&context=jpcrr>.

[24] The body gets rid of this virus in the urine. It can contaminate water in this way.

[25] The body also excretes this virus the urine. It can contaminate water in this way.

[26] “Cryptosporidium,” Minnesota Department of Health, Drinking Water Protection Section, n.d., <http://www.health.state.mn.us/divs/eh/water/factsheet/com/cryptosporidium.html>.

[27] Ben Guarino, “First Evidence Found of Popular Farm Pesticides in Drinking Water,” Washington Post, Apr. 5, 2017, <https://www.washingtonpost.com/news/speaking-of-science/wp/2017/04/05/iowa-scientists-find-first-evidence-of-popular-farm-pesticides-in-drinking-water/>.

[28] Elizabeth Royte, “Tap Water’s Dirty Little Secret,” Huffington Post, Sept. 18, 2008, updated May 25, 2011, <https://www.huffingtonpost.com/elizabeth-royte/tap-waters-dirty-little-s_b_119590.html>.

[29] “Tapped Out?: Are Chlorine’s Beneficial Effects in Drinking Water Offset by Its Links to Cancer?” n.d., <https://www.scientificamerican.com/article/earth-talks-tapped-out/>. The author was talking about the health dangers of chlorine (on which, see above), and continued by noting that you may not avoid the dangers of chlorinated tap water by switching to bottled. “Much of the bottled water for sale in the U.S. comes from public municipal water sources that are often treated with, you guessed it, chlorine.”

[30] Ibid.

[31] Brent Bauer, “What Is BPA, and What Are the Concerns About BPA?” Mayo Clinic, Mar. 11, 2016, <https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/bpa/faq-20058331>.

[32] V. Santhia, N. Sakaiab, E. Ahmada, A. Mustafaa, “Occurrence of Bisphenol A in Surface Water, Drinking Water and Plasma from Malaysia with Exposure Assessment from Consumption of Drinking Water,” Science of The Total Environment, vols 427 & 428, Jun. 15, 2012, pp. 332-338, <https://www.sciencedirect.com/science/article/pii/S0048969712005736>. True, this study was conducted in Malaysia. Given this, some readers may worry that the results are inapplicable to people living in places – e.g., the E.U., U.S., Canada, U.K., etc. – where BPA is being “phased out.” However, number one, BPA’s “…replacements, like fluorene-9-bisphenol, might be just as harmful. …BPA replacements haven’t been adequately tested.” According to Aylin Woodward, “How to Strip 99 Per Cent of Harmful BPA From Water in 30 Minutes,” New Scientist, Aug. 2, 2017, <https://www.newscientist.com/article/2142662-how-to-strip-99-per-cent-of-harmful-bpa-from-water-in-30-minutes/>. Number two, BPA-containing bottles are still used in the U.S., etc. – even though their use is (supposedly) being phased out.

[33] Ibid.

[34] Aylin Woodward, “How to Strip 99 Per Cent of Harmful BPA From Water in 30 Minutes,” New Scientist, Aug. 2, 2017, <https://www.newscientist.com/article/2142662-how-to-strip-99-per-cent-of-harmful-bpa-from-water-in-30-minutes/>.

[35] V. Santhia, N. Sakaiab, E. Ahmada, A. Mustafaa, “Occurrence of Bisphenol A in Surface Water, Drinking Water and Plasma from Malaysia with Exposure Assessment from Consumption of Drinking Water,” Science of The Total Environment, vols 427 & 428, Jun. 15, 2012, pp. 332-338, <https://www.sciencedirect.com/science/article/pii/S0048969712005736>.

[36] “Bacteria in Tap Water Can Be Traced to the Water Treatment Process,” Phys.org, University of Michigan, Aug. 20, 2012, <https://phys.org/news/2012-08-bacteria-treatment.html>.

[37] See, e.g., Tara C. Smith, “‘Raw Water’ Isn’t Better for You—but It Could Definitely Hurt You,” Self, Jan. 11, 2018, <https://www.self.com/story/raw-water-isnt-better-for-youbut-it-could-definitely-hurt-you>.

[38] See Dennis Baumgardner, “Freshwater Fungal Infections,” article 5, Journal of Patient-Centered

Research and Reviews, vol. 4, no. 1, Jan. 31, 2017, p. 33, <https://digitalrepository.aurorahealthcare.org/cgi/viewcontent.cgi?article=1262&context=jpcrr>.

[39] Rick Curtis, The Backpacker’s Field Manual, New York: Random House, 1998; online as “OA Guide to Water Purification,” Princeton Univ., n.d., <http://www.princeton.edu/~oa/manual/water.shtml>.

[40] Aylin Woodward, “How to Strip 99 Per Cent of Harmful BPA From Water in 30 Minutes,” New Scientist, Aug. 2, 2017, <https://www.newscientist.com/article/2142662-how-to-strip-99-per-cent-of-harmful-bpa-from-water-in-30-minutes/>.

[41] “Disinfection with Chlorine,” Centers for Disease Control and Prevention, Jun. 22, 2015, <https://www.cdc.gov/healthywater/drinking/public/chlorine-disinfection.html>.

[42] Rick Curtis, The Backpacker’s Field Manual, New York: Random House, 1998; online as “OA Guide to Water Purification,” Princeton Univ., n.d., <http://www.princeton.edu/~oa/manual/water.shtml>.